Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2026	Jun. 30, 2025
CASH FLOWS FROM OPERATING ACTIVITIES
Net loss	$ (68,908)	$ (94,879)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	8,827	11,028
Depreciation and amortization expense	4,554	6,576
Gain on securities purchase agreement put/call	(17,561)	0
Non-cash lease income	(2,306)	(1,516)
Net amortization and accretion on marketable securities	(1,708)	(2,890)
Change in fair value of success payment liabilities	(752)	(240)
Loss on property and equipment disposals, net	117	3,759
Change in fair value of contingent consideration payable	0	(2,075)
Impairment of long-lived assets	0	1,443
Loss on marketable equity security	0	28
Changes in operating assets and liabilities:
Prepaid expenses, other current assets and other assets	3,325	4,796
Accounts payable	919	(1,885)
Accrued liabilities and other current liabilities	1,041	(13,118)
Other non-current liabilities	20	(223)
Net cash used in operating activities	(72,432)	(89,196)
CASH FLOWS FROM INVESTING ACTIVITIES
Purchases of property and equipment	(345)	(414)
Sales of property and equipment	5	0
Purchases of marketable securities	(90,706)	(165,112)
Maturities of marketable securities	124,040	247,639
Net cash provided by investing activities	32,994	82,113
CASH FLOWS FROM FINANCING ACTIVITIES
Proceeds from employee stock purchase plan	522	184
Proceeds from exercise of stock options	26	0
Net cash provided by financing activities	52,244	184
Net increase (decrease) in cash, cash equivalents and restricted cash	12,806	(6,899)
Cash, cash equivalents and restricted cash at beginning of period	61,766	107,287
Cash, cash equivalents and restricted cash at end of period	74,572	100,388
Represented by:
Cash and cash equivalents	72,985	98,804
Restricted cash	1,587	1,584
Total	74,572	100,388
SUPPLEMENTAL CASH FLOW INFORMATION
Cash paid for amounts included in the measurement of lease liabilities	6,436	6,252
Non-cash investing and financing activities:
Purchases of property and equipment included in accounts payable and accrued liabilities	77	9
Securities Purchase Agreement
CASH FLOWS FROM FINANCING ACTIVITIES
Proceeds from equity issuance/offering	50,000	0
At The Market Offering
CASH FLOWS FROM FINANCING ACTIVITIES
Proceeds from equity issuance/offering	$ 1,696	$ 0