Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025
Statement of Comprehensive Income [Abstract]
Revenue	$ 4	$ 8	$ 6	$ 15
Operating expenses:
Research and development	39,524	34,857	76,128	78,304
General and administrative	9,576	9,786	19,131	23,832
Other operating (income) loss, net	(1,759)	1,062	(3,655)	943
Impairment of long-lived assets	0	1,443	0	1,443
Total operating expenses	47,341	47,148	91,604	104,522
Loss from operations	(47,337)	(47,140)	(91,598)	(104,507)
Interest income, net	2,184	3,276	4,378	7,138
Other income, net	398	1,180	18,312	2,490
Total other income, net	2,582	4,456	22,690	9,628
Net loss	(44,755)	(42,684)	(68,908)	(94,879)
Other comprehensive loss:
Net unrealized loss on marketable securities	(149)	(101)	(400)	(234)
Comprehensive loss	$ (44,904)	$ (42,785)	$ (69,308)	$ (95,113)
Net loss per common share, basic (in dollars per share)	$ (1.92)	$ (2.89)	$ (3.05)	$ (6.42)
Net loss per common share, diluted (in dollars per share)	$ (1.92)	$ (2.89)	$ (3.05)	$ (6.42)
Weighted-average shares used to compute net loss per common share, basic (in shares)	23,364	14,793	22,624	14,774
Weighted-average shares used to compute net loss per common share, diluted (in shares)	23,364	14,793	22,624	14,774