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Income Taxes - Schedule of Reconciliation of Federal Statutory Income Tax Rate (Details)
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Income Tax Disclosure [Abstract]      
U.S. federal statutory tax 21.00% 21.00% 21.00%
State tax, net of federal benefit   4.61% 7.45%
Change in valuation allowance (19.60%) (20.39%) (29.10%)
Stock-based compensation (2.12%) (2.17%) (2.25%)
Tax credits 1.30% 2.23% 2.96%
IPR&D   (0.0534) 0
Other 0.01% 0.06% (0.06%)
Effective income tax rate 0.00% 0.00% 0.00%