Leases - Narrative (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2025 USD ($)	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2019 ft² contract option	Oct. 31, 2024 ft² option	Sep. 30, 2024 ft²	Sep. 30, 2021 USD ($) ft²	May 31, 2021 ft²	Dec. 31, 2018 ft² option
Lessee, Lease, Description [Line Items]
Operating lease cost | $	$ 9,100	$ 9,200	$ 9,000
Variable lease cost | $	$ 6,900	$ 7,100	5,400
Weighted average remaining lease term of operating leases (in years)	4 years 9 months 18 days	5 years 8 months 12 days
Operating lease, weighted average discount rate (as a percent)	8.50%	8.50%
Sonoma sublease income | $	$ 3,601	$ 3,004	2,729
Impairment of long-lived assets | $	1,443	51,297	0
South San Francisco, California
Lessee, Lease, Description [Line Items]
Rentable area (in square feet) | ft²						12,150		11,000
Related Party
Lessee, Lease, Description [Line Items]
Rentable area (in square feet) | ft²							18,000
Related Party | Sonoma
Lessee, Lease, Description [Line Items]
Rentable area (in square feet) | ft²							18,000
Sonoma sublease income | $	$ 1,861	1,861	1,861
Tenant improvements | $							$ 4,600
Building | ImmPACT Bio USA Inc.
Lessee, Lease, Description [Line Items]
Area of space (in square feet) | ft²					26,000
Renewal term (in years)					5 years
Number of options to extend the lease | option					1
Building | Expires in December 2028
Lessee, Lease, Description [Line Items]
Area of space (in square feet) | ft²									34,000
Number of renewal options | option									2
Renewal term (in years)									5 years
Building | Expires in May 2030
Lessee, Lease, Description [Line Items]
Area of space (in square feet) | ft²				73,000
Number of renewal options | option				2
Renewal term (in years)				90 months
Number of operating lease agreements | contract				2
Building | Expires In March 2031
Lessee, Lease, Description [Line Items]
Area of space (in square feet) | ft²				108,000
Renewal term (in years)				10 years
Right Of Use Asset
Lessee, Lease, Description [Line Items]
Impairment of long-lived assets | $		$ 12,600	$ 0