Consolidated Statements of Stockholders’ Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning balance, (in shares) at Dec. 31, 2021		242,738,000
Beginning balance at Dec. 31, 2021	$ 929,787	$ 24	$ 1,515,748	$ (1,623)	$ (584,362)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation (in shares)		2,600,000
Stock-based compensation	81,924		81,924
Issuance of common stock upon exercise of stock options (in shares)		3,601,000
Issuance of common stock upon exercise of stock options	9,577	$ 1	9,576
Issuance of common stock under employee stock purchase plan (in share)		475,000
Issuance of common stock under employee stock purchase plan	1,519		1,519
Issuance of common stock in connection with restricted stock units, net of tax (in share)		153,000
Issuance of common stock in connection with restricted stock units, net of tax	(461)		(461)
Other comprehensive (loss) Income	(5,976)			(5,976)
Net loss	(183,118)				(183,118)
Ending balance, (in shares) at Dec. 31, 2022		249,567,000
Ending balance at Dec. 31, 2022	833,252	$ 25	1,608,306	(7,599)	(767,480)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	47,084		47,084
Issuance of common stock upon exercise of stock options (in shares)		2,996,000
Issuance of common stock upon exercise of stock options	306		306
Issuance of common stock under employee stock purchase plan (in share)		987,000
Issuance of common stock under employee stock purchase plan	1,894		1,894
Issuance of common stock in connection with restricted stock units, net of tax (in share)		408,000
Issuance of common stock in connection with restricted stock units, net of tax	(457)		(457)
Other comprehensive (loss) Income	7,505			7,505
Net loss	$ (234,632)				(234,632)
Ending balance, (in shares) at Dec. 31, 2023	253,957,709	253,958,000
Ending balance at Dec. 31, 2023	$ 654,952	$ 25	1,657,133	(94)	(1,002,112)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	$ 33,144		33,144
Issuance of common stock upon exercise of stock options (in shares)	1,245,836	1,246,000
Issuance of common stock upon exercise of stock options	$ 154		154
Issuance of common stock under employee stock purchase plan (in share)		955,000
Issuance of common stock under employee stock purchase plan	1,248		1,248
Issuance of common stock in connection with restricted stock units, net of tax (in share)		1,217,000
Issuance of common stock in connection with restricted stock units, net of tax	(76)		(76)
Issuance of common stock as payment for acquisition of IPR&D asset (in shares)		37,500,000
Issuance of common stock as payment for acquisition of IPR&D asset	36,011	$ 4	36,007
Other comprehensive (loss) Income	385			385
Net loss	$ (342,994)				(342,994)
Ending balance, (in shares) at Dec. 31, 2024	294,875,546	294,876,000
Ending balance at Dec. 31, 2024	$ 382,824	$ 29	$ 1,727,610	$ 291	$ (1,345,106)