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Property and Equipment, Net
 12 Months Ended
Dec. 31, 2024
Property, Plant and Equipment [Abstract]  
Property and Equipment, Net Property and Equipment, Net
Property and equipment, net, consisted of the following (in thousands):
December 31,
20242023
Leasehold improvements
$79,613 $118,319 
Laboratory equipment
36,106 33,368 
Computer equipment and software
1,805 1,672 
Furniture and fixtures
1,114 814 
Construction in progress
241 128 
Property and equipment, at cost
118,879 154,301 
Less: Accumulated depreciation and amortization
(70,679)(51,647)
Total property and equipment, net
$48,200 $102,654 
Depreciation and amortization expense was $19.4 million, $20.2 million and $18.0 million for the years ended December 31, 2024, 2023 and 2022, respectively.
During the year ended December 31, 2024, the Company recorded impairment losses of $38.7 million for leasehold improvements. The Company did not record any impairment losses in 2023 and 2022. See Note 5, Impairment of Long‑Lived Assets, for further information.