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License, Collaboration, and Success Payment Agreements - Narrative (Details)
3 Months Ended 6 Months Ended
Jun. 30, 2024
USD ($)
Jun. 30, 2023
USD ($)
Jun. 30, 2024
USD ($)
Jun. 30, 2023
USD ($)
Dec. 31, 2023
USD ($)
Oct. 31, 2020
USD ($)
$ / shares
Dec. 31, 2019
USD ($)
Dec. 31, 2018
USD ($)
$ / shares
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Research and development expense $ 40,261,000 $ 47,471,000 $ 83,435,000 $ 92,101,000        
Series A Convertible Preferred Stock                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Convertible preferred stock, par value (in dollars per share) | $ / shares           $ 1.83   $ 1.83
Fred Hutch | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Annual license maintenance payments               $ 50,000
Aggregate research payments due               $ 12,000,000
Term of collaborative arrangement for research               6 years
Research and development expense 100,000 100,000 200,000 400,000        
Aggregate success payments 0   0          
Term of success payment agreement               9 years
Trigger period from IPO date               1 year
Trigger period thereafter               2 years
Fair value of potential success payments due 300,000   300,000   $ 700,000      
Success payment expense (reversal) (700,000) 500,000 (300,000) (600,000)        
Fred Hutch | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Multiple of initial equity value at issuance               10
Aggregate success payments               $ 10,000,000
Per share common stock price required for payment (in dollars per share) | $ / shares               $ 18.29
Fred Hutch | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Multiple of initial equity value at issuance               50
Aggregate success payments               $ 200,000,000
Per share common stock price required for payment (in dollars per share) | $ / shares               $ 91.44
Stanford | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Annual license maintenance payments             $ 50,000  
Aggregate research payments due           $ 12,000,000    
Term of collaborative arrangement for research           4 years    
Research and development expense 700,000 700,000 1,500,000 1,500,000        
Aggregate success payments 0   0          
Term of success payment agreement           9 years    
Trigger period from IPO date           1 year    
Trigger period thereafter           2 years    
Fair value of potential success payments due 700,000   700,000   1,100,000      
Success payment expense (reversal) (800,000) $ 600,000 (300,000) $ 0        
Success payment liability $ 700,000   $ 700,000   $ 900,000      
Stanford | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | License                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Potential milestone payments due             2,500,000  
Stanford | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Multiple of initial equity value at issuance           10    
Aggregate success payments           $ 10,000,000    
Per share common stock price required for payment (in dollars per share) | $ / shares           $ 18.29    
Stanford | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Multiple of initial equity value at issuance           50    
Aggregate success payments           $ 200,000,000    
Per share common stock price required for payment (in dollars per share) | $ / shares           $ 91.44    
Stanford | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum | License                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Potential milestone payments due             $ 3,700,000