Cash Equivalents and Marketable Securities - Schedule of Fair Value and Amortized Cost of Cash Equivalents and Marketable Securities (Details) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022	Mar. 31, 2022
Marketable Securities [Line Items]
Amortized Cost	$ 109,426	$ 123,554	$ 222,596
Amortized Cost	646,353	702,094
Gross Unrealized Gains	229	4
Gross Unrealized Losses	(4,108)	(7,603)
Fair Value	642,474	694,495
Classified as:
Cash equivalents	83,876	107,780
Marketable securities	503,343	516,598
Marketable securities, non-current	55,255	70,117
Total cash equivalents and marketable securities	642,474	694,495
U.S. Treasury securities
Marketable Securities [Line Items]
Amortized Cost	285,287	277,056
Gross Unrealized Gains	91	0
Gross Unrealized Losses	(2,849)	(5,257)
Fair Value	282,529	271,799
U.S. government agency securities
Marketable Securities [Line Items]
Amortized Cost	124,533	135,460
Gross Unrealized Gains	102	1
Gross Unrealized Losses	(749)	(1,416)
Fair Value	123,886	134,045
Corporate debt securities
Marketable Securities [Line Items]
Amortized Cost	182,196	221,608
Gross Unrealized Gains	36	3
Gross Unrealized Losses	(510)	(930)
Fair Value	181,722	220,681
Money market funds
Marketable Securities [Line Items]
Amortized Cost	54,337	67,970
Fair Value	$ 54,337	$ 67,970