Related-Party Transactions (Details) ft² in Thousands	1 Months Ended	12 Months Ended
	Mar. 31, 2020 shares	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($) shares	Sep. 30, 2021 USD ($) ft²
Related Party Transaction [Line Items]
Due to related parties, current		$ 0	$ 4,988,000
Due to related parties, noncurrent		0	79,665,000
Revenue recognized from related parties		84,653,000	10,509,000	$ 7,756,000
Repurchase of convertible preferred stock (in shares) | shares				547,000
Common Stock
Related Party Transaction [Line Items]
Repurchase of common stock (in shares) | shares				2,032,000
Series A Convertible Preferred Stock
Related Party Transaction [Line Items]
Repurchase of convertible preferred stock (in shares) | shares	546,806
Affiliated Entity | Sublease with Sonoma
Related Party Transaction [Line Items]
Rentable area (in square feet) | ft²					18
Tenant improvements					$ 4,600,000
Due to related parties, current		500,000	500,000
Due to related parties, noncurrent		3,500,000	4,000,000
Revenue recognized from related parties		2,600,000	1,800,000
Sublease Income		1,900,000	600,000
Affiliated Entity | Stock Repurchase from Related Party
Related Party Transaction [Line Items]
Repurchase of common stock (in shares) | shares	2,032,166
Affiliated Entity | Stock Repurchase from Related Party | Common Stock
Related Party Transaction [Line Items]
Repurchase of common stock (in shares) | shares	2,032,166
Affiliated Entity | Stock Repurchase from Related Party | Series A Convertible Preferred Stock
Related Party Transaction [Line Items]
Repurchase of convertible preferred stock (in shares) | shares	546,806
Investor | GSK Agreement
Related Party Transaction [Line Items]
Due to related parties, current		0	5,000,000
Due to related parties, noncurrent		0	79,700,000
Revenue recognized from related parties		$ 84,700,000	$ 10,500,000	$ 7,800,000
Investor | GSK Agreement | Lyell Immunopharma | Minimum | GSK
Related Party Transaction [Line Items]
Ownership interest (as a percent)		10.00%