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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Statement of Comprehensive Income [Abstract]      
Revenues [1] $ 84,683 $ 10,650 $ 7,756
Operating expenses:      
Research and development 159,188 138,693 182,243
General and administrative 117,307 89,057 46,881
Other operating income, net (4,754) (2,324) (9,431)
Total operating expenses 271,741 225,426 219,693
Loss from operations (187,058) (214,776) (211,937)
Interest income, net 7,053 1,165 5,939
Other income (expense), net 1,887 (161) 1,526
Impairment of other investments (5,000) (36,447) 0
Total other income (loss), net 3,940 (35,443) 7,465
Net loss (183,118) (250,219) (204,472)
Other comprehensive loss:      
Net unrealized loss on marketable securities (5,976) (1,879) (198)
Comprehensive loss (189,094) (252,098) (204,670)
Net loss attributed to common stockholders:      
Net loss (183,118) (250,219) (204,472)
Deemed dividends upon repurchase of convertible preferred stock 0 0 (3,582)
Net loss attributed to common stockholders $ (183,118) $ (250,219) $ (208,054)
Net loss per common share, basic (in dollars per share) $ (0.74) $ (1.84) $ (15.69)
Net loss per common share, diluted (in dollars per share) $ (0.74) $ (1.84) $ (15.69)
Weighted-average shares used to compute net loss per common share, basic (in shares) 247,080 135,918 13,258
Weighted-average shares used to compute net loss per common share, diluted (in shares) 247,080 135,918 13,258
[1] Includes related-party revenue of $84,653, $10,509 and $7,756 for the years ended December 31, 2022, 2021 and 2020, respectively.