Cash Equivalents and Marketable Securities - Schedule of Fair Value and Amortized Cost of Cash Equivalents and Marketable Securities (Details) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Marketable Securities [Line Items]
Amortized Cost	$ 123,554	$ 293,828	$ 140,406
Amortized Cost	702,094	876,356
Gross Unrealized Gains	4	4
Gross Unrealized Losses	(7,603)	(1,627)
Fair Value	694,495	874,733
Classified as:
Cash equivalents	107,780	270,236
Marketable securities	516,598	320,966
Marketable securities, non-current	70,117	283,531
Total cash equivalents and marketable securities	694,495	874,733
U.S. Treasury securities
Marketable Securities [Line Items]
Amortized Cost	277,056	290,909
Gross Unrealized Gains	0	2
Gross Unrealized Losses	(5,257)	(1,205)
Fair Value	271,799	289,706
U.S. government agency securities
Marketable Securities [Line Items]
Amortized Cost	135,460	93,864
Gross Unrealized Gains	1	2
Gross Unrealized Losses	(1,416)	(240)
Fair Value	134,045	93,626
Corporate debt securities
Marketable Securities [Line Items]
Amortized Cost	221,608	285,338
Gross Unrealized Gains	3	0
Gross Unrealized Losses	(930)	(182)
Fair Value	220,681	285,156
Money market funds
Marketable Securities [Line Items]
Amortized Cost	67,970	206,245
Fair Value	$ 67,970	$ 206,245