Condensed Consolidated Balance Sheets - USD ($) $ in Thousands		Sep. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents		$ 116,311	$ 293,828
Marketable securities		531,821	320,966
Prepaid expenses and other current assets		11,613	11,492
Total current assets		659,745	626,286
Restricted cash		279	466
Marketable securities, non-current		102,519	283,531
Other investments		42,001	47,001
Property and equipment, net		125,727	120,098
Operating lease right-of-use assets		44,084	46,541
Other non-current assets		2,914	3,483
Total assets		977,269	1,127,406
Current liabilities:
Accounts payable		4,795	3,207
Accrued liabilities and other current liabilities		23,568	29,057
Success payment liabilities		11,663	9,486
Deferred revenue	[1]	11,191	4,988
Total current liabilities		51,217	46,738
Operating lease liabilities, non-current		64,636	66,650
Deferred revenue, non-current	[2]	37,163	79,665
Other non-current liabilities		4,227	4,566
Total liabilities		157,243	197,619
Commitments and contingencies (Note 12)
Stockholders’ equity:
Preferred stock, $0.0001 par value; 10,000 shares authorized at September 30, 2022 and December 31, 2021; zero shares issued and outstanding at September 30, 2022 and December 31, 2021		0	0
Common stock, $0.0001 par value; 500,000 shares authorized at September 30, 2022 and December 31, 2021; 249,240 and 242,738 shares issued and outstanding at September 30, 2022 and December 31, 2021, respectively		25	24
Additional paid-in capital		1,589,080	1,515,748
Accumulated other comprehensive loss		(9,996)	(1,623)
Accumulated deficit		(759,083)	(584,362)
Total stockholders’ equity		820,026	929,787
Total liabilities and stockholders’ equity		$ 977,269	$ 1,127,406

[1] Including amounts from a related-party of $11,191 and $4,988 as of September 30, 2022 and December 31, 2021, respectively.

[2] Including amounts from a related-party of $37,163 and $79,665 as of September 30, 2022 and December 31, 2021, respectively.