The amount by which the fair value of an investment is less than the amortized cost basis or carrying amount of that investment at the balance sheet date and the decline in fair value is deemed to be other than temporary, before considering whether or not such amount is recognized in earnings or other comprehensive income.

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 320
-SubTopic 10
-Section 45
-Paragraph 8A
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Amount of investments classified as other.

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 944
-SubTopic 210
-Section S99
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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Other Investments (Details) - USD ($) $ in Thousands	3 Months Ended
Other Investments (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Mar. 31, 2022	Nov. 30, 2020
Schedule of Investments [Line Items]
Other investments	$ 47,001	$ 47,001
Variable Interest Entity, Not Primary Beneficiary \| Outpace Bio Inc
Schedule of Investments [Line Items]
Noncontrolling interest in variable interest entity	13,000	$ 13,000	$ 13,000
PACT
Schedule of Investments [Line Items]
Other investments	36,400
Impairment of other investments	$ 36,400