Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 222,596	$ 293,828
Marketable securities	391,316	320,966
Prepaid expenses and other current assets	11,793	11,492
Total current assets	625,705	626,286
Restricted cash	279	466
Marketable securities, non-current	224,118	283,531
Other investments	47,001	47,001
Property and equipment, net	125,707	120,098
Operating lease right-of-use assets	45,725	46,541
Other non-current assets	3,568	3,483
Total assets	1,072,103	1,127,406
Current liabilities:
Accounts payable	6,510	3,207
Accrued liabilities and other current liabilities	22,686	29,057
Success payment liabilities	5,635	9,486
Deferred revenue	6,224	4,988
Total current liabilities	41,055	46,738
Operating lease liabilities, non-current	67,475	66,650
Deferred revenue, non-current	77,871	79,665
Other non-current liabilities	4,453	4,566
Total liabilities	190,854	197,619
Commitments and contingencies (Note 12)
Stockholders’ equity:
Preferred stock, $0.0001 par value; 10,000 shares authorized at March 31, 2022 and December 31, 2021; zero shares issued and outstanding at March 31, 2022 and December 31, 2021	0	0
Common stock, $0.0001 par value; 500,000 shares authorized at March 31, 2022 and December 31, 2021; 245,423 and 242,738 shares issued and outstanding at March 31, 2022 and December 31, 2021, respectively	25	24
Additional paid-in capital	1,540,330	1,515,748
Accumulated other comprehensive loss	(6,600)	(1,623)
Accumulated deficit	(652,506)	(584,362)
Total stockholders’ equity	881,249	929,787
Total liabilities and stockholders’ equity	$ 1,072,103	$ 1,127,406