Related-party Transactions	3 Months Ended
	Mar. 31, 2022
Related Party Transactions [Abstract]
Related-party Transactions	Related-party TransactionsIn September 2021, the Company entered into a sublease with Sonoma, whereby the Company agreed to sublease approximately 18,000 square feet of space in South San Francisco, California currently leased by the Company. Dr. Klausner serves as a member of the board of directors of Sonoma and he and certain holders of more than 5% of our outstanding common stock are also stockholders of Sonoma. As a part of the sublease, a $4.6 million tenant improvement contribution payment was made by Sonoma, which will be recognized over the term of the sublease. As of March 31, 2022, accrued liabilities and other current liabilities of $0.5 million and other non-current liabilities of $3.9 million were in connection with the sublease with Sonoma. Income of $0.7 million was recognized in other operating income, net for the three months ended March 31, 2022. See Note 7, Leases, for more detail on the Sonoma sublease.The Company is party to the GSK Agreement, who is a holder of more than 10% of the Company’s outstanding common stock. See Note 3, License, Collaboration and Success Payment Agreements. Deferred revenue of $6.2 million and $5.0 million as of March 31, 2022 and December 31, 2021, respectively, and deferred revenue, net of current portion of $77.9 million and $79.7 million as of March 31, 2022 and December 31, 2021, respectively, were in connection with the GSK Agreement. Revenue recognized in connection with the GSK agreement was $0.6 million and $2.4 million for the three months ended March 31, 2022 and 2021, respectively.