X0306 4 2021-06-21 0 0001806952 Lyell Immunopharma, Inc. LYEL 0001591178 Klausner Richard C/O LYELL IMMUNOPHARMA, INC. 400 EAST JAMIE COURT, SUITE 301 SOUTH SAN FRANCISCO CA 94080 1 1 0 0 Executive Chairman Common Stock 2021-06-21 4 C 0 3765842 A 3765842 I Lyell Investors, LLC Common Stock 2967834 D Series A Convertible Preferred Stock 2021-06-21 4 C 0 3765842 0.00 D Common Stock 3765842 0 I Lyell Investors, LLC The Issuer's Series A Convertible Preferred Stock converted into Common Stock on a 1-for-1 basis and had no expiration date. The Reporting Person is a manager of Lyell Investors, LLC (Lyell Investors) and may be deemed to share the power to direct the disposition and vote of the shares held by Lyell Investors. The Reporting Person disclaims beneficial ownership of all shares held by Lyell Investors except to any pecuniary interest therein /s/ Heather Turner, as Attorney-in-fact 2021-06-23