X0206 3 2021-06-16 0 0001806952 Lyell Immunopharma, Inc. LYEL 0001480212 Bishop Hans Edgar C/O LYELL IMMUNOPHARMA, INC. 400 EAST JAMIE COURT, SUITE 301 SOUTH SAN FRANCISCO CA 94080 1 0 0 0 Common Stock 3000000 D Series A Convertible Preferred Stock 1.8288 Common Stock 546806 D Option (right to buy) 0.10 2028-11-05 Common Stock 1163038 D 1/4 of the shares vested on August 1, 2019, with the remaining shares to vest in equal monthly installments over the following thirty-six months. The Series A Convertible Preferred Stock is convertible at any time, at the Reporting Person's election, has no expiration date, and will automatically convert to shares of the Issuer's Common Stock immediately prior to the closing of the Issuer's initial public offering on a 1-for-1 basis. 1/4 of the option shares vested on September 20, 2019, with the remaining option shares to vest in equal monthly installments over the following thirty-six months. The option provides for an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase. /s/ Heather D. Turner, as Attorney-in-fact 2021-06-16