Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2026	Sep. 30, 2025
Cash flows from operating activities
Net loss	$ (128,177)	$ (81,144)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation expense	843	846
Stock-based compensation	17,439	9,769
Non-cash net gain on lease termination	(5,108)
Change in fair value of warrant liability		463
Non-cash change in fair value of term loan	(235)	627
Debt issuance costs expensed under fair value option		147
Non-cash lease expense	796	959
Other	155	264
Changes in operating assets and liabilities:
Prepaid expenses and other assets	1,175	401
Accounts payable	2,282	1,973
Accrued expenses and other liabilities	(3,387)	3,615
Deferred revenue		(4,288)
Net cash used in operating activities	(114,217)	(66,368)
Cash flows from investing activities
Purchase of research and development license	(3,000)
Purchase of property, plant and equipment	(466)	(488)
Other		131
Net cash used in investing activities	(3,466)	(357)
Cash flows from financing activities
Proceeds from issuance of common stock and pre-funded warrants from underwritten public offering, net of underwriting discounts and sales commissions and other offering costs	215,717	215,716
Prepayment of 2023 Trinity term loan		(40,612)
Proceeds from 2025 Trinity term loan, net		49,853
Payment of shelf registration costs		(33)
Proceeds from common stock issuances under ESPP	463	159
Proceeds from stock option exercises	2,137	197
Other	(166)	(247)
Net cash provided by financing activities	218,151	225,033
Net increase in cash, cash equivalents and restricted cash	100,468	158,308
Cash, cash equivalents and restricted cash at the beginning of the period	322,531	141,636
Cash, cash equivalents and restricted cash at the end of the period	422,999	299,944
Cash and cash equivalents	422,834	297,344
Restricted cash	165	2,600
Supplemental disclosure of cash flow information:
Cash paid for interest	4,331	3,949
Supplemental disclosure of noncash investing and financing activities:
Property, plant and equipment in accounts payable and accrued expenses	171	41
Right-of-use assets obtained in exchange for lease liabilities	$ 159
Offering costs not yet paid		25
Proceeds allocated to Success Fee liability		$ 217