Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Underwritten Public Offering	ATM Agreement	Common Stock	Common Stock Underwritten Public Offering	Common Stock ATM Agreement	Additional Paid-in Capital	Additional Paid-in Capital Underwritten Public Offering	Additional Paid-in Capital ATM Agreement	Accumulated Deficit	Accumulated Other Comprehensive Loss
Balance at Dec. 31, 2023	$ 74,937			$ 2			$ 587,942			$ (513,007)
Balance, shares at Dec. 31, 2023				186,960,193
Stock-based compensation	13,103						13,103
Issuance of common stock and pre-funded warrants, upon closing of underwritten public offering, net of underwriting discounts and commissions, and other offering costs		$ 76,694						$ 76,694
Issuance of common stock and pre-funded warrants, upon closing of underwritten public offering, net of underwriting discounts and commissions, and other offering costs, shares					17,596,113
Issuance of common stock upon vesting and settlement of restricted stock units, net	(9)						(9)
Issuance of common stock upon vesting and settlement of restricted stock units, net, shares				234,198
Issuance of common stock under ESPP	89						89
Issuance of common stock under ESPP, shares				93,970
Issuance of common stock upon exercise of stock options	40						40
Issuance of common stock upon exercise of stock options, shares				58,832
Gain (loss) on instrument-specific credit risk	(4,031)										$ (4,031)
Net loss	(89,298)									(89,298)
Balance at Dec. 31, 2024	$ 71,525			$ 2			677,859			(602,305)	(4,031)
Balance, shares at Dec. 31, 2024	204,943,306			204,943,306
Stock-based compensation	$ 13,298						13,298
Issuance of common stock and pre-funded warrants, upon closing of underwritten public offering, net of underwriting discounts and commissions, and other offering costs		$ 215,646			$ 1			$ 215,645
Issuance of common stock and pre-funded warrants, upon closing of underwritten public offering, net of underwriting discounts and commissions, and other offering costs, shares					57,777,777
Issuance of common stock, net of sales commissions and other offering costs			$ 48,435						$ 48,435
Issuance of common stock, net of sales commissions and other offering costs, shares						10,230,186
Issuance of common stock upon exercise of pre-funded warrants, shares				9,607,145
Issuance of common stock upon exercise warrants	1,862						1,862
Issuance of common stock upon exercise warrants, shares				316,667
Issuance of common stock upon vesting and settlement of restricted stock units, net	(51)						(51)
Issuance of common stock upon vesting and settlement of restricted stock units, net, shares				1,299,156
Issuance of common stock under ESPP	159						159
Issuance of common stock under ESPP, shares				123,151
Issuance of common stock upon exercise of stock options	1,220						1,220
Issuance of common stock upon exercise of stock options, shares				754,260
Gain (loss) on instrument-specific credit risk	3,839										3,839
Net loss	(108,995)									(108,995)
Balance at Dec. 31, 2025	$ 246,938			$ 3			$ 958,427			$ (711,300)	$ (192)
Balance, shares at Dec. 31, 2025	285,051,648			285,051,648