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Stock-Based Compensation - Schedule of Stock Option Activity (Details) - Stock Options - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2023
Dec. 31, 2021
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Outstanding. Stock Options, Beginning Balance 6,158,078  
Options granted, Stock Options 1,043,371  
Options cancelled or forfeited, Stock Options (1,765,389)  
Options expired, Stock Options (123,198)  
Outstanding. Stock Options, Ending Balance 5,312,862  
Options exercisable at March 31, 2023, Stock Options 1,401,840  
Options granted, Weighted Average Exercise Price $ 1.18  
Options cancelled or forfeited, Weighted Average Exercise Price 11.50  
Options expired, Weighted Average Exercise Price 24.00  
Outstanding, Weighted Average Exercise Price, Ending balance 9.58 $ 11.84
Options exercisable at March 31, 2023, Weighted Average Exercise Price $ 22.18  
Outstanding, Weighted Average Remaining Contractual Life 8 years 2 months 12 days 8 years 10 months 24 days
Options exercisable at March 31, 2023, Weighted Average Remaining Contractual Life 4 years 7 months 6 days  
Outstanding, Aggregate Intrinsic Value, Beginning Balance $ 62