Significant Accounting Policies - Summary of Effect of the Adoption of ASC 842 on Statement of Operation and Cash Flows (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Operating expenses:
Research and development	$ 12,514	$ 38,182
Other income (expense):
Interest expense	(1,374)	(672)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation expense	331	260
Non-cash lease expense	300	309
Changes in operating assets and liabilities:
Accrued expenses and other current liabilities		(779)
Cash flows from financing activities
Other	$ (33)	(233)
Supplemental disclosure of noncash investing and financing activities:
Right-of-use assets obtained in exchange for lease liabilities		$ 18,634
Accounting Standards Update [Extensible Enumeration]		Accounting Standards Update 2016-02 [Member]
Previously ASC 842
Operating expenses:
Research and development		$ 37,799
Other income (expense):
Interest expense		(849)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation expense		257
Changes in operating assets and liabilities:
Accrued expenses and other current liabilities		(538)
Cash flows from financing activities
Other		(368)
ASC 842 Adjustments
Operating expenses:
Research and development		383
Other income (expense):
Interest expense		177
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation expense		3
Non-cash lease expense		309
Changes in operating assets and liabilities:
Accrued expenses and other current liabilities		(241)
Cash flows from financing activities
Other		135
Supplemental disclosure of noncash investing and financing activities:
Right-of-use assets obtained in exchange for lease liabilities		$ 18,634