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Loan with Silicon Valley Bank - Additional Information (Details)
1 Months Ended 12 Months Ended
Aug. 12, 2021
USD ($)
Program
Dec. 31, 2021
USD ($)
Dec. 31, 2022
USD ($)
Debt Instrument [Line Items]      
Debt instrument, maturity date Aug. 01, 2026    
Percentage of interest rate 7.00%   11.25%
Percentage of prepayment of facility 7.50%    
Warrants associated with loan facility $ 0    
Exit fee recorded as debt discount     $ 3,000,000.0
Percentage of annual default interest rate 5.00%    
Interest expense related to term loan     3,700,000
Prime Rate      
Debt Instrument [Line Items]      
Debt instrument, basis spread on variable rate 3.75%    
Term Loan      
Debt Instrument [Line Items]      
Proceeds from term loan $ 30,000,000.0 $ 10,000,000.0  
Through December 31, 2021 | Term Loan      
Debt Instrument [Line Items]      
Maximum borrowing capacity $ 40,000,000.0    
Debt instrument, maturity date Dec. 31, 2021    
January 1, 2022 until September 30, 2022 | Term Loan      
Debt Instrument [Line Items]      
Maximum borrowing capacity $ 20,000,000.0   $ 20,000,000.0
Debt instrument, maturity start date Jan. 01, 2022    
Debt instrument, maturity end date Sep. 30, 2022   Sep. 30, 2022
Number of distinct and active clinical stage | Program 3    
Proceeds from term loan     $ 0
October 1, 2022 until March 31, 2023 | Term Loan      
Debt Instrument [Line Items]      
Maximum borrowing capacity $ 20,000,000.0    
Debt instrument, maturity start date Oct. 01, 2022    
Debt instrument, maturity end date Mar. 31, 2023    
Number of distinct and active clinical stage | Program 3    
April 1, 2023 until December 31, 2023 | Term Loan      
Debt Instrument [Line Items]      
Maximum borrowing capacity $ 20,000,000.0    
Debt instrument, maturity start date Apr. 01, 2023    
Debt instrument, maturity end date Dec. 31, 2023    
Through August 13, 2022      
Debt Instrument [Line Items]      
Percentage of prepayment premium 2.00%    
Through August 13, 2023      
Debt Instrument [Line Items]      
Percentage of prepayment premium 1.00%