Consolidated Statements of Operations - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Income Statement [Abstract]
Revenues	$ 2,502,000
Operating expenses:
Research and development	91,169,000	$ 131,943,000
General and administrative	37,360,000	41,324,000
Impairment of long-lived assets	36,420,000	0
Total operating expenses	164,949,000	173,267,000
Loss from operations	(162,447,000)	(173,267,000)
Other income (expense):
Interest income	249,000	172,000
Interest expense	(3,798,000)	(1,428,000)
Other expense	(18,000)
Total other expense, net	(3,567,000)	(1,256,000)
Net loss	$ (166,014,000)	$ (174,523,000)
Net loss per common share, basic	$ (3.78)	$ (4.64)
Net loss per common share, diluted	$ (3.78)	$ (4.64)
Weighted average common shares outstanding, basic	43,952,015	37,650,566
Weighted average common shares outstanding, diluted	43,952,015	37,650,566