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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (Unaudited) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Operating expenses:        
Research and development $ 71,385 $ 40,159 $ 198,947 $ 114,014
General and administrative 23,680 14,368 61,654 41,594
Total operating expenses 95,065 54,527 260,601 155,608
Loss from operations (95,065) (54,527) (260,601) (155,608)
Interest income (expense), net 2,706 13 3,668 38
Other income (expense), net (7,579) (7,545) (1,770) (10,709)
Loss before income taxes (99,938) (62,059) (258,703) (166,279)
Net loss $ (99,938) $ (62,059) $ (258,703) $ (166,279)
Net loss per share, basic $ (0.66) $ (0.43) $ (1.73) $ (1.25)
Net loss per share, diluted $ (0.66) $ (0.43) $ (1.73) $ (1.25)
Weighted-average shares used in calculating net loss per share, basic 152,304,645 144,022,109 149,544,252 132,971,450
Weighted-average shares used in calculating net loss per share, diluted 152,304,645 144,022,109 149,544,252 132,971,450
Comprehensive loss:        
Net loss $ (99,938) $ (62,059) $ (258,703) $ (166,279)
Other comprehensive income (loss)        
Changes in fair value attributable to instrument-specific credit risk (1,364) (533) 9,466 (533)
Unrealized gains (losses) on securities available-for-sale (1,430)   (3,286)  
Total other comprehensive income (loss) (2,794) (533) 6,180 (533)
Comprehensive loss $ (102,732) $ (62,592) $ (252,523) $ (166,812)