X0306 4 2021-09-24 0 0001805387 Cerevel Therapeutics Holdings, Inc. CERE 0001216068 DEKKERS MARIJN E C/O CEREVEL THERAPEUTICS HOLDINGS, INC. 222 JACOBS STREET, SUITE 200 CAMBRIDGE MA 02141 1 0 0 0 Common Stock 2021-09-24 4 M 0 14270 A 42810 D Common Stock 633350 I See footnote Restricted Stock Units 2021-09-24 4 M 0 14270 0.00 D Common Stock 14270 0 D The shares reported in this transaction represent Restricted Stock Units ("RSUs") granted under the Cerevel Therapeutics Holdings, Inc. 2020 Equity Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's common stock. Shares held by Novalis LifeSciences Investments I, L.P., or Novalis LifeSciences. Marijn Dekkers, the Manager of the general partner of Novalis LifeSciences, has sole voting and dispositive power over the shares held by Novalis LifeSciences and, as a result, may be deemed to share beneficial ownership of the shares held by Novalis LifeSciences. 14,270 RSUs vested on September 24, 2021, the third anniversary of the vesting commencement date of September 24, 2018. /s/ Mark Bodenrader, as Attorney-in-Fact 2021-09-28