<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13D" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13D/A</submissionType>
    <previousAccessionNumber>0001214659-25-004920</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: Zentree Investments Ltd -->
          <cik>0001946012</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>2</amendmentNo>
      <securitiesClassTitle>Class A Common Stock, par value $0.0001 per share</securitiesClassTitle>
      <dateOfEvent>03/28/2025</dateOfEvent>
      <previouslyFiledFlag>false</previouslyFiledFlag>
      <issuerInfo>
        <issuerCIK>0001804591</issuerCIK>
        <issuerCUSIP>90138Q306</issuerCUSIP>
        <issuerName>23andMe Holding Co.</issuerName>
        <address>
          <com:street1>870 MARKET STREET</com:street1>
          <com:street2>ROOM 415</com:street2>
          <com:city>SAN FRANCISCO</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94102</com:zipCode>
        </address>
      </issuerInfo>
      <authorizedPersons>
        <notificationInfo>
          <personName>Richard Magides</personName>
          <personPhoneNum>65 69557665</personPhoneNum>
          <personAddress>
            <com:street1>c/o Zentree Investment Mgmt Pte Ltd</com:street1>
            <com:street2>18 Robinson Road Level 15-01</com:street2>
            <com:city>Singapore</com:city>
            <com:stateOrCountry>U0</com:stateOrCountry>
            <com:zipCode>048547</com:zipCode>
          </personAddress>
        </notificationInfo>
      </authorizedPersons>
    </coverPageHeader>
    <reportingPersons>
      <reportingPersonInfo>
        <reportingPersonCIK>0001946012</reportingPersonCIK>
        <reportingPersonNoCIK>N</reportingPersonNoCIK>
        <reportingPersonName>Zentree Investments Limited</reportingPersonName>
        <fundType>WC</fundType>
        <legalProceedings>N</legalProceedings>
        <citizenshipOrOrganization>E9</citizenshipOrOrganization>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>3699236.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>3699236.00</sharedDispositivePower>
        <aggregateAmountOwned>3699236.00</aggregateAmountOwned>
        <isAggregateExcludeShares>N</isAggregateExcludeShares>
        <percentOfClass>18.2</percentOfClass>
        <typeOfReportingPerson>OO</typeOfReportingPerson>
      </reportingPersonInfo>
      <reportingPersonInfo>
        <reportingPersonNoCIK>Y</reportingPersonNoCIK>
        <reportingPersonName>Richard Magides</reportingPersonName>
        <fundType>PF</fundType>
        <legalProceedings>N</legalProceedings>
        <citizenshipOrOrganization>X0</citizenshipOrOrganization>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>3699236.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>3699236.00</sharedDispositivePower>
        <aggregateAmountOwned>3699236.00</aggregateAmountOwned>
        <isAggregateExcludeShares>N</isAggregateExcludeShares>
        <percentOfClass>18.2</percentOfClass>
        <typeOfReportingPerson>IN</typeOfReportingPerson>
      </reportingPersonInfo>
    </reportingPersons>
    <items1To7>
      <item1>
        <securityTitle>Class A Common Stock, par value $0.0001 per share</securityTitle>
        <issuerName>23andMe Holding Co.</issuerName>
        <issuerPrincipalAddress>
          <com:street1>870 MARKET STREET</com:street1>
          <com:street2>ROOM 415</com:street2>
          <com:city>SAN FRANCISCO</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94102</com:zipCode>
        </issuerPrincipalAddress>
        <commentText>Optional Comments up to 20,000 characters.</commentText>
      </item1>
      <item2>
        <filingPersonName>Zentree Investments Limited
Richard Magides</filingPersonName>
        <principalBusinessAddress>Zentree Investments Limited
c/o Zentree Investment Management Pte Ltd
18 Robinson Road
Level 15-01
Singapore 048547

Richard Magides
c/o Zentree Investment Management Pte Ltd
18 Robinson Road
Level 15-01
Singapore 048547</principalBusinessAddress>
        <principalJob>Zentree Investments Limited:  An exempt company incorporated in the Cayman Islands  Richard Magides: Director</principalJob>
        <hasBeenConvicted>Neither of the Reporting Persons has, during the last five years, been convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors).</hasBeenConvicted>
        <convictionDescription>Neither of the Reporting Persons has, during the last five years, been a party to a civil proceeding of a judicial or administrative body of competent jurisdiction and as a result of such proceeding was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, federal or state securities laws or finding any violation with respect to such laws;</convictionDescription>
        <citizenship>Zentree Investments Limited: Citizenship The Cayman Islands
Richard Magides: Citizenship British</citizenship>
      </item2>
      <item3>
        <fundsSource>Zentree Investments Limited:
Available net assets were used to purchase the shares of Class A Common Stock referred to in this Schedule 13D.

Richard Magides:
Personal funds were used to purchase the shares of Class A Common Stock referred to in this Schedule 13D.</fundsSource>
      </item3>
      <item4>
        <transactionPurpose>We want to ensure that minority investors are afforded a voice, thereby ensuring fair treatment. We seek to prevent the sale of the company at an unreasonable price and advocate for more prudent management of the company's costs. Additionally, we appeal that Class A and Class B shares be granted equal rights. We urge the management to act in the best interests of all shareholders and to address any conflicts of interest between management and investors.</transactionPurpose>
      </item4>
      <item5>
        <percentageOfClassSecurities>Percentage of class: 18.2%
As of the close of business on March 28, 2025, Zentree Investments Limited and Mr. Magides may be deemed to have beneficially owned 3,699,236 Class A Common Stock of the Issuer outstanding (see Item 5(b) below). This percentage was calculated based on 20,340,344 shares of Class A Common Stock, outstanding as of March 6, 2025, as provided by the Issuer.</percentageOfClassSecurities>
        <numberOfShares>As of the close of business on March 28, 2025, Zentree Investments Limited and Richard Magides beneficially owned a total of 3,699,236 Class A Common Stock of the Issuer, representing 3,699,236 Class A Common Stock nominal value $0.0001 per share. Of this amount Zentree Investments Limited owns 566,643 shares and Mr. Magides owns 3,132,593 shares. Richard Magides is the director of Zentree Investments Limited and may be deemed to have shared voting control and investment discretion over securities owned by Zentree Investments Limited.</numberOfShares>
        <transactionDesc>Richard Magides
Zentree Investments Limited

Refer to exhibit 99.1</transactionDesc>
        <listOfShareholders>Not applicable</listOfShareholders>
        <date5PercentOwnership>Not applicable</date5PercentOwnership>
      </item5>
      <item6>
        <contractDescription>We have no contracts, arrangements, understandings or relationships with respect to securities of the issuer. We only have limited contact with the investor relations representative.</contractDescription>
      </item6>
      <item7>
        <filedExhibits>Exhibit 99.1 - Transaction Description</filedExhibits>
      </item7>
    </items1To7>
    <signatureInfo>
      <signaturePerson>
        <signatureReportingPerson>Zentree Investments Limited</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Richard Magides</signature>
          <title>Director</title>
          <date>04/01/2025</date>
        </signatureDetails>
      </signaturePerson>
      <signaturePerson>
        <signatureReportingPerson>Richard Magides</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Richard Magides</signature>
          <title>Director</title>
          <date>04/01/2025</date>
        </signatureDetails>
      </signaturePerson>
    </signatureInfo>
  </formData>

</edgarSubmission>
