The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM 88579Y101   3,279,600 30,000 SH   SOLE N/A 30,000 0 0
ACLARIS THERAPEUTICS INC COM 00461U105   1,028,369 979,399 SH   SOLE N/A 979,399 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108   59,647 79,234 SH   SOLE N/A 79,234 0 0
ADVISORSHARES TR PURE US CANNABIS 00768Y453   4,696,700 670,000 SH   SOLE N/A 670,000 0 0
AGNICO EAGLE MINES LTD COM 008474108   18,990,386 346,224 SH   SOLE N/A 346,224 0 0
ALAMOS GOLD INC NEW COM CL A 011532108   4,310,400 320,000 SH   SOLE N/A 320,000 0 0
ALCOA CORP COM 013872106   21,250,000 625,000 SH   SOLE N/A 625,000 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102   6,059,732 78,180 SH   SOLE N/A 78,180 0 0
ALICO INC COM 016230104   1,019,109 35,045 SH   SOLE N/A 35,045 0 0
ANGLOGOLD ASHANTI PLC COM SHS G0378L100   3,953,851 211,549 SH   SOLE N/A 211,549 0 0
APPLE INC COM 037833100   21,178,300 110,000 SH Put SOLE N/A 110,000 0 0
B2GOLD CORP COM 11777Q209   3,397,000 1,075,000 SH   SOLE N/A 1,075,000 0 0
BAIDU INC SPON ADR REP A 056752108   5,565,790 46,736 SH   SOLE N/A 46,736 0 0
BARRICK GOLD CORP COM 067901108   4,477,275 247,500 SH   SOLE N/A 247,500 0 0
BLUEBIRD BIO INC COM 09609G100   207,000 150,000 SH   SOLE N/A 150,000 0 0
BRIGHTCOVE INC COM 10921T101   142,450 55,000 SH   SOLE N/A 55,000 0 0
BUZZFEED INC CLASS A COM 12430A102   125,000 500,000 SH   SOLE N/A 500,000 0 0
CHIMERIX INC COM 16934W106   4,213,511 4,377,674 SH   SOLE N/A 4,377,674 0 0
CITIGROUP INC COM NEW 172967424   1,028,800 20,000 SH   SOLE N/A 20,000 0 0
COMPASS MINERALS INTL INC COM 20451N101   506,400 20,000 SH   SOLE N/A 20,000 0 0
CUE BIOPHARMA INC COM 22978P106   903,519 342,242 SH   SOLE N/A 342,242 0 0
DOLLAR GEN CORP NEW COM 256677105   1,699,375 12,500 SH   SOLE N/A 12,500 0 0
EARGO INC COM NEW 270087208   129,500 50,000 SH   SOLE N/A 50,000 0 0
EMEREN GROUP LTD SPONSORED ADS 75971T301   2,272,316 832,350 SH   SOLE N/A 832,350 0 0
ESPERION THERAPEUTICS INC NE COM 29664W105   728,490 243,642 SH   SOLE N/A 243,642 0 0
ETF MANAGERS TR PRIME JUNIR SLVR 26924G102   6,190,000 619,000 SH   SOLE N/A 619,000 0 0
FATE THERAPEUTICS INC COM 31189P102   8,165,273 2,183,228 SH   SOLE N/A 2,183,228 0 0
FERRARI N V COM N3167Y103   33,843,000 100,000 SH Put SOLE N/A 100,000 0 0
FIRST MAJESTIC SILVER CORP COM 32076V103   307,500 50,000 SH   SOLE N/A 50,000 0 0
FMC CORP COM NEW 302491303   2,837,250 45,000 SH   SOLE N/A 45,000 0 0
FORUM ENERGY TECHNOLOGIES IN COM 34984V209   1,563,451 70,521 SH   SOLE N/A 70,521 0 0
GALAPAGOS NV SPON ADR 36315X101   274,144 6,744 SH   SOLE N/A 6,744 0 0
GOSSAMER BIO INC COM 38341P102   255,500 280,000 SH   SOLE N/A 280,000 0 0
HANESBRANDS INC COM 410345102   1,784,000 400,000 SH   SOLE N/A 400,000 0 0
HERON THERAPEUTICS INC COM 427746102   3,785,008 2,226,475 SH   SOLE N/A 2,226,475 0 0
HERTZ GLOBAL HLDGS INC COM NEW 42806j700   1,142,900 110,000 SH   SOLE N/A 110,000 0 0
INVESCO QQQ TR COM 46090E103   5,119,000 12,500 SH Put SOLE N/A 12,500 0 0
JASPER THERAPEUTICS INC COM 471871103   196,905 249,563 SH   SOLE N/A 249,563 0 0
JD.COM INC SPON ADR CL A 47215P106   4,766,850 165,000 SH   SOLE N/A 165,000 0 0
KODIAK SCIENCES INC COM 50015M109   1,157,054 380,610 SH   SOLE N/A 380,610 0 0
MAG SILVER CORP COM 55903Q104   2,615,090 251,200 SH   SOLE N/A 251,200 0 0
MARAVAI LIFESCIENCES HLDGS I COM CL A 56600D107   2,038,426 311,210 SH   SOLE N/A 311,210 0 0
MEDICAL PPTYS TRUST INC COM 58463J304   982,000 200,000 SH Call SOLE N/A 200,000 0 0
MEREO BIOPHARMA GROUP PLC SPON ADS 589492107   1,562,701 676,494 SH   SOLE N/A 676,494 0 0
MP MATERIALS CORP COM CL A 553368101   496,250 25,000 SH   SOLE N/A 25,000 0 0
NEKTAR THERAPEUTICS COM 640268108   3,374,964 5,973,387 SH   SOLE N/A 5,973,387 0 0
NEW GOLD INC CDA COM 644535106   2,157,519 1,477,753 SH   SOLE N/A 1,477,753 0 0
NEWMONT CORP COM 651639106   11,837,540 286,000 SH   SOLE N/A 286,000 0 0
NOVAVAX INC COM NEW 670002401   322,315 67,149 SH   SOLE N/A 67,149 0 0
NOVOCURE LTD ORD SHS G6674U108   676,866 45,336 SH   SOLE N/A 45,336 0 0
NOW INC COM 67011P100   1,457,688 128,771 SH   SOLE N/A 128,771 0 0
NVIDIA CORPORATION COM 67066G104   7,131,168 14,400 SH Put SOLE N/A 14,400 0 0
ONEMAIN HLDGS INC COM 68268W103   2,460,000 50,000 SH Call SOLE N/A 50,000 0 0
ORIC PHARMACEUTICALS INC COM 68622P109   2,576,000 280,000 SH   SOLE N/A 280,000 0 0
PALO ALTO NETWORKS INC COM 697435105   7,372,000 25,000 SH Put SOLE N/A 25,000 0 0
PAN AMERN SILVER CORP COM 697900108   11,436,172 700,309 SH   SOLE N/A 700,309 0 0
PAYPAL HLDGS INC COM 70450Y103   10,065,099 163,900 SH   SOLE N/A 163,900 0 0
PELOTON INTERACTIVE INC CL A COM 70614W100   913,500 150,000 SH   SOLE N/A 150,000 0 0
PERRIGO CO PLC SHS G97822103   643,600 20,000 SH   SOLE N/A 20,000 0 0
PFIZER INC COM 717081103   5,758,000 200,000 SH   SOLE N/A 200,000 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109   749,382 378,476 SH   SOLE N/A 378,476 0 0
RINGCENTRAL INC CL A 76680R206   1,358,000 40,000 SH   SOLE N/A 40,000 0 0
SIBANYE STILLWATER LTD SPONSORED ADR 82575P107   5,209,314 959,358 SH   SOLE N/A 959,358 0 0
SPROTT PHYSICAL SILVER TR TR UNIT 85207K107   1,858,400 230,000 SH   SOLE N/A 230,000 0 0
STONECO LTD COM CL A G85158106   5,156,832 286,014 SH   SOLE N/A 286,014 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106   522,150 295,000 SH   SOLE N/A 295,000 0 0
TELEFONAKTIEBOLAGET LM ERICS ADR B SEK 10 294821608   472,500 75,000 SH   SOLE N/A 75,000 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   14,274,612 1,367,300 SH   SOLE N/A 1,367,300 0 0
TUSIMPLE HLDGS INC CL A 90089L108   2,680,439 3,053,587 SH   SOLE N/A 3,053,587 0 0
VANDA PHARMACEUTICALS INC COM 921659108   358,700 85,000 SH   SOLE N/A 85,000 0 0
VANECK ETF TRUST JUNIOR GOLD MINE 92189F791   8,226,470 217,000 SH   SOLE N/A 217,000 0 0
VEON LTD SPONSORED ADS 91822M502   468,860 23,800 SH   SOLE N/A 23,800 0 0
VIATRIS INC COM 92556V106   16,207,474 1,496,535 SH   SOLE N/A 1,496,535 0 0
VIATRIS INC COM 92556V106   1,446,888 133,600 SH Call SOLE N/A 133,600 0 0
WALGREENS BOOTS ALLIANCE INC COM 931427108   4,242,875 162,500 SH   SOLE N/A 162,500 0 0
YANDEX N V SHS CLASS A N97284108   1,564,500 105,000 SH   SOLE N/A 105,000 0 0
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101   12,860,384 178,840 SH   SOLE N/A 178,840 0 0
ZYMEWORKS INC COM 98985Y108   3,636,500 350,000 SH   SOLE N/A 350,000 0 0