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License Agreements and Asset Purchase Agreements (Details) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Oct. 31, 2022
Aug. 31, 2021
Jan. 31, 2021
Oct. 31, 2020
Nov. 30, 2019
Aug. 31, 2019
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Jul. 31, 2022
Feb. 28, 2019
License Agreements and Asset Purchase Agreements                      
Cost of product sold             $ 121,236 $ 83,481 $ 55,518    
Accrued Sales Based Trademark and Royalties             40,419 25,367      
All Countries Excluding Greater China | HBS-102 | Asset Purchase Agreement with ConSynance Therapeutics                      
License Agreements and Asset Purchase Agreements                      
Consideration transferred   $ 3,500                  
Payment for intellectual property upon preclinical milestones   1,750                  
Payment for intellectual property upon developmental milestones   19,000                  
Payment for intellectual property upon regulatory milestones   44,000                  
Payment for intellectual property upon sales milestones   $ 110,000                  
Bioprojet                      
License Agreements and Asset Purchase Agreements                      
Licensing agreement milestone fees           $ 2,000          
License agreement milestone payments paid         $ 75,000 2,000          
License agreement, additional milestone payment due           102,000          
Accrued Sales Based Trademark and Royalties             40,419 25,367      
Bioprojet | Upon Acceptance by FDA of Pitolisant's                      
License Agreements and Asset Purchase Agreements                      
License agreement, milestone payment due                     $ 50,000
License agreement, upfront non-refundable licensing fees paid $ 30,000                    
License agreement, maximum additional milestone payment due                   $ 155,000  
Bioprojet | Upon Acceptance by FDA of Pitolisant's | Research and development expense                      
License Agreements and Asset Purchase Agreements                      
License agreement, upfront non-refundable licensing fees paid               30,000      
Bioprojet | Upon FDA Approval of WAKIX                      
License Agreements and Asset Purchase Agreements                      
License agreement, milestone payment due           77,000          
Licensing agreement milestone fees           $ 2,000          
License agreement milestone payments paid     $ 100,000 $ 2,000              
Bioprojet | Sales-based, trademark and tiered royalties                      
License Agreements and Asset Purchase Agreements                      
Cost of product sold             111,685 $ 77,107 $ 50,957    
Bioprojet | United States                      
License Agreements and Asset Purchase Agreements                      
Amount of Aggregate Net Sales Attaining             500,000        
Bioprojet | Attaining $500,000 Aggregate Net Sales | United States | Upon FDA Approval of WAKIX                      
License Agreements and Asset Purchase Agreements                      
Final payment paid             $ 40,000