<SEC-DOCUMENT>0001140361-23-045410-index.html : 20230927
<SEC-HEADER>0001140361-23-045410.hdr.sgml : 20230927
<ACCEPTANCE-DATETIME>20230927081213
ACCESSION NUMBER:		0001140361-23-045410
CONFORMED SUBMISSION TYPE:	SC TO-T/A
PUBLIC DOCUMENT COUNT:		3
FILED AS OF DATE:		20230927
DATE AS OF CHANGE:		20230927

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Zynerba Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001621443
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				260389433
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC TO-T/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-88971
		FILM NUMBER:		231281863

	BUSINESS ADDRESS:	
		STREET 1:		80 W. LANCASTER AVENUE
		STREET 2:		SUITE 300
		CITY:			DEVON
		STATE:			PA
		ZIP:			19333
		BUSINESS PHONE:		484-581-7505

	MAIL ADDRESS:	
		STREET 1:		80 W. LANCASTER AVENUE
		STREET 2:		SUITE 300
		CITY:			DEVON
		STATE:			PA
		ZIP:			19333

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Zynerba Pharmeceuticals, Inc.
		DATE OF NAME CHANGE:	20141003

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Harmony Biosciences Holdings, Inc.
		CENTRAL INDEX KEY:			0001802665
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				822279923
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC TO-T/A

	BUSINESS ADDRESS:	
		STREET 1:		630 W GERMANTOWN PIKE
		STREET 2:		SUITE 215
		CITY:			PLYMOUTH MEETING
		STATE:			PA
		ZIP:			19462
		BUSINESS PHONE:		(484) 539-9800

	MAIL ADDRESS:	
		STREET 1:		630 W GERMANTOWN PIKE
		STREET 2:		SUITE 215
		CITY:			PLYMOUTH MEETING
		STATE:			PA
		ZIP:			19462
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC TO-T/A
<SEQUENCE>1
<FILENAME>ef20011271_scto-ta.htm
<DESCRIPTION>SC TO-T/A
<TEXT>
Document 1 - file: ef20011271_scto-ta.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.(A)(5)(B)
<SEQUENCE>2
<FILENAME>ef20011271_ex99-a5b.htm
<DESCRIPTION>EXHIBIT 99.(A)(5)(B)
<TEXT>
Document 2 - file: ef20011271_ex99-a5b.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>image00001.jpg
<TEXT>
Document 3 - file: image00001.jpg

</DOCUMENT>
</SEC-DOCUMENT>