SCHEDULE 13G/A 0001193125-21-022692 0001821461 XXXXXXXX LIVE 1 Common Stock, par value $0.00001 per share 12/31/2024 0001802665 Harmony Biosciences Holdings, Inc. 413197104 630 W Germantown Pike Plymouth Meeting PA 19462 Rule 13d-1(d) Marshman Fund Trust II FL 6051120.00 0.00 6051120.00 0.00 6051120.00 N 10.6 OO Harmony Biosciences Holdings, Inc. 630 W. Germantown Pike, Plymouth Meeting, PA, 19462 Marshman Fund Trust II 2340 Collins Avenue, Suite 403, Miami Beach, FL 33139 Florida Y The information contained on the cover page to this Schedule 13G is incorporated by reference into this Item 4. The ownership information presented herein represents beneficial ownership of common stock (the "Common Stock") as of December 31, 2024, based upon 57,030,897 shares of Common Stock outstanding as of October 31, 2024, as disclosed in the Issuer's Prospectus Supplement on Form 424B7 filed with the Securities and Exchange Commission on October 31, 2024. The reporting person is the record holder of 6,051,120 shares of Common Stock. 10.6 6,051,120 0 6,051,120 0 Y Y Y Y Y Y Marshman Fund Trust II /s/ Charles Harris 02/10/2025