<SEC-DOCUMENT>0001104659-21-136263-index.html : 20211109
<SEC-HEADER>0001104659-21-136263.hdr.sgml : 20211109
<ACCEPTANCE-DATETIME>20211109160210
ACCESSION NUMBER:		0001104659-21-136263
CONFORMED SUBMISSION TYPE:	S-3ASR
PUBLIC DOCUMENT COUNT:		7
FILED AS OF DATE:		20211109
DATE AS OF CHANGE:		20211109
EFFECTIVENESS DATE:		20211109

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Harmony Biosciences Holdings, Inc.
		CENTRAL INDEX KEY:			0001802665
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				822279923
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3ASR
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-260905
		FILM NUMBER:		211391955

	BUSINESS ADDRESS:	
		STREET 1:		630 W GERMANTOWN PIKE
		STREET 2:		SUITE 215
		CITY:			PLYMOUTH MEETING
		STATE:			PA
		ZIP:			19462
		BUSINESS PHONE:		(484) 539-9800

	MAIL ADDRESS:	
		STREET 1:		630 W GERMANTOWN PIKE
		STREET 2:		SUITE 215
		CITY:			PLYMOUTH MEETING
		STATE:			PA
		ZIP:			19462
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3ASR
<SEQUENCE>1
<FILENAME>tm2132214-1_s3asr.htm
<DESCRIPTION>S-3ASR
<TEXT>
Document 1 - file: tm2132214-1_s3asr.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.3
<SEQUENCE>2
<FILENAME>tm2132214d2_ex4-3.htm
<DESCRIPTION>EXHIBIT 4.3
<TEXT>
Document 2 - file: tm2132214d2_ex4-3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>3
<FILENAME>tm2132214d2_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 3 - file: tm2132214d2_ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>4
<FILENAME>tm2132214d2_ex23-2.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
Document 4 - file: tm2132214d2_ex23-2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>lg_harmonybio-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: lg_harmonybio-4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>tm2132214d2_ex5-1img01.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: tm2132214d2_ex5-1img01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>tm2132214d2_ex5-1img02.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: tm2132214d2_ex5-1img02.jpg

</DOCUMENT>
</SEC-DOCUMENT>