<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
<headerData>
<submissionType>SCHEDULE 13G</submissionType>
<filerInfo>
<filer>
<filerCredentials>
<cik>0002064899</cik>
<ccc>XXXXXXXX</ccc>
</filerCredentials>
</filer>
<liveTestFlag>LIVE</liveTestFlag>


</filerInfo>
</headerData>
<formData>
<coverPageHeader>
<securitiesClassTitle>Ordinary shares, no par value</securitiesClassTitle>
<eventDateRequiresFilingThisStatement>03/05/2025</eventDateRequiresFilingThisStatement>
<issuerInfo>
<issuerCik>0001801834</issuerCik>
<issuerName>PAINREFORM LTD.</issuerName>
<issuerCusip>M77798144</issuerCusip>
<issuerPrincipalExecutiveOfficeAddress>
<com:street1>65 Igal Alon Street</com:street1>
<com:city>Tel Aviv</com:city>
<com:stateOrCountry>L3</com:stateOrCountry>
<com:zipCode>6744316</com:zipCode>
</issuerPrincipalExecutiveOfficeAddress>
</issuerInfo>
<designateRulesPursuantThisScheduleFiled>
<designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
</designateRulesPursuantThisScheduleFiled>
</coverPageHeader>
<coverPageHeaderReportingPersonDetails>

<reportingPersonName>Blade Ranger Ltd.</reportingPersonName>
<citizenshipOrOrganization>L3</citizenshipOrOrganization>
<reportingPersonBeneficiallyOwnedNumberOfShares>
<soleVotingPower>189370</soleVotingPower>
<sharedVotingPower>0</sharedVotingPower>
<soleDispositivePower>189370</soleDispositivePower>
<sharedDispositivePower>0</sharedDispositivePower>
</reportingPersonBeneficiallyOwnedNumberOfShares>
<reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
<aggregateAmountExcludesCertainSharesFlag>Y</aggregateAmountExcludesCertainSharesFlag>
<classPercent>9.99</classPercent>
<typeOfReportingPerson>CO</typeOfReportingPerson>
<comments>(Row 1) A special committee (the "Special Committee"), comprised of the Chairman of the Board of Directors of Blade Ranger Ltd. ("Blade"), the controlling shareholder of Blade and the Chief Executive Officer of Blade, has power to vote and/or dispose of the ordinary shares, no par value per share (the "Ordinary Shares"), of PainReform Ltd. (the "Issuer") beneficially owned by Blade. A majority vote of members of the Special Committee is required for any action in connection with the Ordinary Shares held by Blade, and no single member has a veto right. Each of the members of the Special Committee disclaims beneficial ownership of the Ordinary Shares held by Blade.   &#13;
&#13;
(Row 5) As of April 23, 2025, Blade is the beneficial owner of 189,370 Ordinary Shares consisting of (i) 178,769 Ordinary Shares; and (ii) pre-funded warrants to purchase up to 10,601 Ordinary Shares exercisable within 60 days of April 23, 2025. In addition, Blade is the owner of (i) pre-funded warrants to purchase up to 213,191 Ordinary Shares, (ii) pre-funded warrants to purchase up to 685,004 Ordinary Shares, exercisable upon the achievement of certain milestones, and (iii) warrants to purchase up to 2,175,130 Ordinary Shares, exercisable upon the achievement of certain milestones, which are not exercisable due to a beneficial ownership limitation of 9.99% of the Issuer's issued and outstanding Ordinary Shares.&#13;
&#13;
(Row 11) Based on a total of 1,885,001 Ordinary Shares, outstanding as of April 23, 2025, as reported by the Issuer to the Reporting Persons (as defined below).</comments>
</coverPageHeaderReportingPersonDetails>
<items>
<item1>
<issuerName>PAINREFORM LTD.</issuerName>
<issuerPrincipalExecutiveOfficeAddress>65 Igal Alon Street, Tel Aviv, Israel, 6744316</issuerPrincipalExecutiveOfficeAddress>
</item1>
<item2>
<filingPersonName>Blade Ranger Ltd.</filingPersonName>
<principalBusinessOfficeOrResidenceAddress>Hayasmin 1st Ramat Efal, Ramat Gan, Israel</principalBusinessOfficeOrResidenceAddress>
<citizenship>Israel</citizenship>
</item2>
<item3>
<notApplicableFlag>Y</notApplicableFlag>
</item3>
<item4>
<amountBeneficiallyOwned>189370</amountBeneficiallyOwned>
<classPercent>9.99</classPercent>
<numberOfSharesPersonHas>
<solePowerOrDirectToVote>189370</solePowerOrDirectToVote>
<sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
<solePowerOrDirectToDispose>189370</solePowerOrDirectToDispose>
<sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
</numberOfSharesPersonHas>
</item4>
<item5>
<notApplicableFlag>Y</notApplicableFlag>
</item5>
<item6>
<notApplicableFlag>Y</notApplicableFlag>
</item6>
<item7>
<notApplicableFlag>Y</notApplicableFlag>
</item7>
<item8>
<notApplicableFlag>Y</notApplicableFlag>
</item8>
<item9>
<notApplicableFlag>Y</notApplicableFlag>
</item9>
<item10>
<notApplicableFlag>N</notApplicableFlag>
<certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
</item10>
</items>
<signatureInformation>
<reportingPersonName>Blade Ranger Ltd.</reportingPersonName>
<signatureDetails>
<signature>/s/ Ronen Tsioni</signature>
<title>Ronen Tsioni</title>
<date>04/24/2025</date>
</signatureDetails>
<signatureDetails>
<signature>/s/ Sefi Hatuka</signature>
<title>Sefi Hatuka</title>
<date>04/24/2025</date>
</signatureDetails>
</signatureInformation>
</formData>
</edgarSubmission>
