X0306 4 2022-01-28 0 0001801777 Applied Molecular Transport Inc. AMTI 0001813286 Mahmood Tahir Ph.D. C/O APPLIED MOLECULAR TRANSPORT INC. 450 EAST JAMIE COURT SOUTH SAN FRANCISCO CA 94080 1 1 0 0 Chief Executive Officer Common Stock 2022-01-28 4 P 0 3000 7.88 A 3000 D Common Stock 176657 I By Irrevocable Trust Common Stock 334632 I By GRAT Common Stock 3088711 I By Living Trust These shares are held directly by The Mahmood 2017 Irrevocable Trust for which the Reporting Person serves as trustee and over which shares the Reporting Person hold voting and dispositive power. These shares are held directly by the Tahir Mahmood 2019 Annuity Trust for which the Reporting Person serves as trustee and over which shares the Reporting Person holds voting and dispositive power. Includes 10,368 shares transferred from the Tahir Mahmood 2019 Annuity Trust since the last filing by the Reporting Person. These shares are held directly by the Mahmood-Shamsi Living Trust Agreement for which the Reporting Person and spouse serve as co-trustees and over which shares the Reporting Person and his spouse hold voting and dispositive power. /s/ Brandon Hants Attorney-in-Fact for Tahir Mahmood 2022-01-31