Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the reference to our firm under the caption “Experts” and to the use of our report dated April 20, 2020, in Amendment No.1 to the Registration Statement (Form F-1 No. 333-238232) and related Prospectus of Legend Biotech Corporation dated May 29, 2020.

/s/ Ernst & Young Hua Ming LLP

Shanghai, the People’s Republic of China

May 29, 2020