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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Cash flows from operating activities    
Net loss $ (21,439) $ (38,349)
Adjustment to reconcile net loss to net cash used in operating activities:    
Depreciation of equipment 21 269
Gain on sale of equipment   (64)
Stock-based compensation 3,239 5,427
Issuance of common stock in connection with vesting of restricted stock units 93  
Issuance of preferred and common stock in connection with an Asset Purchase Agreement 1,890  
Amortization of premiums and discounts on marketable securities 70 (431)
Amortization of right of use lease asset 160 561
Accretion of lease liability 10 46
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 954 65
Other assets, noncurrent 970 1,148
Accounts payable (1,325) (1,648)
Accrued expenses and other current liabilities (3,139) (3,335)
Operating lease liabilities (170) (600)
Other liabilities, noncurrent 43  
Net cash used in operating activities (18,623) (36,911)
Cash flows from investing activities    
Purchases of marketable securities   (25,937)
Proceeds from sale of marketable securities 11,650 48,184
Proceeds from the sale of equipment   83
Net cash provided by investing activities 11,650 22,330
Cash flows from financing activities    
Proceeds from issuance of common stock, net of issuance costs   2,876
Net cash provided by financing activities   2,876
Net decrease in cash and cash equivalents (6,973) (11,705)
Effect of exchange rate changes on cash and cash equivalents (317) 384
Cash and cash equivalents, beginning of year 21,465 32,786
Cash and cash equivalents, end of year 14,175 $ 21,465
Supplemental disclosures of noncash activities:    
Operating lease liability arising from obtaining right-of-use assets $ 75