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Goodwill and Intangible Assets - Intangible Assets (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2022
Dec. 31, 2021
Goodwill and Intangible Assets    
Gross amount of amortizable intangible assets $ 27,700 $ 27,700
Accumulated amortization of intangible assets 16,400 15,900
Increase (Decrease) in intangible assets due to foreign currency translation adjustments 3  
Estimated annual amortization expense, intangible assets, 2022 2,100  
Estimated annual amortization expense, intangible assets, 2023 2,000  
Estimated annual amortization expense, intangible assets, 2024 1,900  
Estimated annual amortization expense, intangible assets, 2025 1,700  
Estimated annual amortization expense, intangible assets, 2026 1,600  
Indefinite-lived intangible assets related to in-process R&D acquired in a business combination $ 919 $ 919