0001085146-25-003293.txt : 20250515 0001085146-25-003293.hdr.sgml : 20250515 20250515160107 ACCESSION NUMBER: 0001085146-25-003293 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20250331 FILED AS OF DATE: 20250515 DATE AS OF CHANGE: 20250515 EFFECTIVENESS DATE: 20250515 FILER: COMPANY DATA: COMPANY CONFORMED NAME: 5AM Venture Management, LLC CENTRAL INDEX KEY: 0001799883 ORGANIZATION NAME: EIN: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-19757 FILM NUMBER: 25952360 BUSINESS ADDRESS: STREET 1: 4 EMBARCADERO CENTER, SUITE 3110 CITY: SAN FRANCISCO STATE: CA ZIP: 94111 BUSINESS PHONE: (415) 993-8565 MAIL ADDRESS: STREET 1: 4 EMBARCADERO CENTER, SUITE 3110 CITY: SAN FRANCISCO STATE: CA ZIP: 94111 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false false false 0001799883 XXXXXXXX 03-31-2025 03-31-2025 false 5AM Venture Management, LLC

4 EMBARCADERO CENTER, SUITE 3110 SAN FRANCISCO CA 94111

13F HOLDINGS REPORT 028-19757 000160395 801-120173 N Lauren A. Daniel 415-993-8570 /s/Lauren A. Daniel San Francisco CA 05-15-2025 0 31 264407625 false INFORMATION TABLE 2 infotable.xml INFORMATION TABLE ADVERUM BIOTECHNOLOGIES INC COM NEW 00773U207 BBG006D9MR26 2367080 541666 SH SOLE 541666 0 0 ALECTOR INC COM 014442107 BBG00N0PL214 1224884 995841 SH SOLE 995841 0 0 ANAPTYSBIO INC COM 032724106 BBG0026ZDHT8 6650256 357733 SH SOLE 357733 0 0 ARTIVA BIOTHERAPEUTICS INC COM 04317A107 BBG00VPZJ0G8 7059912 2353304 SH SOLE 2353304 0 0 BIOHAVEN LTD COM G1110E107 BBG017BXV3R8 11514487 478972 SH SOLE 478972 0 0 CAMP4 THERAPEUTICS CORP COM 13463J101 BBG00L2CHQ99 11711660 2927915 SH SOLE 2927915 0 0 CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 BBG001S7QN20 9025451 497270 SH SOLE 497270 0 0 CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 BBG01081FC68 11948989 830945 SH SOLE 830945 0 0 CIDARA THERAPEUTICS INC COM NEW 171757206 BBG006R5MFV3 1221857 56725 SH SOLE 56725 0 0 DIANTHUS THERAPEUTICS INC COM 252828108 BBG00FB2NQ15 18642678 1027711 SH SOLE 1027711 0 0 ENLIVEN THERAPEUTICS INC COM 29337E102 BBG00CP3BDF2 26026347 1322477 SH SOLE 1322477 0 0 ENTRADA THERAPEUTICS INC COM 29384C108 BBG00MTSMC25 39851746 4408379 SH SOLE 4408379 0 0 ERASCA INC COM 29479A108 BBG00MTSR892 7405403 5405404 SH SOLE 5405404 0 0 EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209 BBG001SNLCD2 5691000 1050000 SH SOLE 1050000 0 0 GH RESEARCH PLC ORDINARY SHARES G3855L106 BBG011BQC422 6316495 572665 SH SOLE 572665 0 0 MERSANA THERAPEUTICS INC COM 59045L106 BBG001TZ57P0 449181 1305000 SH SOLE 1305000 0 0 MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 BBG00XQZQVP7 11029969 282313 SH SOLE 282313 0 0 PHARVARIS N V COM N69605108 BBG00YYCW2H3 12522320 797600 SH SOLE 797600 0 0 PRAXIS PRECISION MEDICINES I COM NEW 74006W207 BBG00W9LF2H4 6437900 170000 SH SOLE 170000 0 0 PROTARA THERAPEUTICS INC COM STK 74365U107 BBG001ZLYSK1 3408000 800000 SH SOLE 800000 0 0 RALLYBIO CORP COM 75120L100 BBG011PFKG07 2376309 3630724 SH SOLE 3630724 0 0 SCPHARMACEUTICALS INC COM 810648105 BBG00J24RT22 3157702 1200647 SH SOLE 1200647 0 0 SILENCE THERAPEUTICS PLC ADS 82686Q101 BBG00WVTHQK3 1342884 476200 SH SOLE 476200 0 0 SKYE BIOSCIENCE INC COM NEW 83086J200 BBG00433H0D8 15761937 9913168 SH SOLE 9913168 0 0 SURROZEN INC COM NEW 86889P208 BBG00XY94SB2 3614600 310000 SH SOLE 310000 0 0 TECTONIC THERAPEUTIC INC COM 878972108 BBG00DJ4T7F9 9061499 511660 SH SOLE 511660 0 0 TYRA BIOSCIENCES INC COM 90240B106 BBG00RCQD9F9 8735471 939298 SH SOLE 939298 0 0 VIKING THERAPEUTICS INC COM 92686J106 BBG006LGV887 4578671 189593 SH SOLE 189593 0 0 VIRIDIAN THERAPEUTICS INC COM 92790C104 BBG002H24301 9929301 736595 SH SOLE 736595 0 0 VOR BIOPHARMA INC COM 929033108 BBG00NBJRDV3 4564536 6361723 SH SOLE 6361723 0 0 ZENTALIS PHARMACEUTICALS INC COM 98943L107 BBG00R2K8TG4 779100 490000 SH SOLE 490000 0 0