Consolidated Statements of Changes in Stockholders' (Deficit) Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Accumulated Other Comprehensive Income (Loss)
Beginning balance at Dec. 31, 2022	$ 103,900	$ 4	$ 502,613	$ (399,118)	$ 401
Beginning balance, Shares at Dec. 31, 2022		1,716,923
Issuance of common stock upon exercise of stock options	23		23
Issuance of common stock upon exercise of stock options, shares		680
Issuance of common stock related to ESPP purchase	551		551
Issuance of common stock related to ESPP purchase, shares		29,084
Issuance of common stock in connection with PIPE offering, net of offering costs	18,644	$ 3	18,641
Issuance of common stock in connection with PIPE offering, net of offering costs,shares		1,257,168
Issuance of pre-funded warrants in connection with PIPE offering, net of offering costs	48,079		48,079
Costs related to the PIPE offering	(4,300)		(4,300)
Stock-based compensation expense related to employee stock awards	11,799		11,799
Stock-based compensation expense related to employee stock purchases	853		853
Vesting of early exercised common stock options	66		66
Other comprehensive income (loss)	144				144
Net loss	(87,679)			(87,679)
Ending balance at Dec. 31, 2023	92,080	$ 7	578,325	(486,797)	545
Ending balance, Shares at Dec. 31, 2023		3,003,855
Issuance of common stock related to ESPP purchase	436		436
Issuance of common stock related to ESPP purchase, shares		32,958
Issuance of common stock upon exercise of pre-funded warrants	3	$ 1	2
Issuance of common stock upon exercise of pre-funded warrants, shares		800,613
Issuance of common stock upon exercise of common warrants	1,361		1,361
Issuance of common stock upon exercise of pre-funded warrants, shares		22,024
Issuance of common stock from RSU vesting, shares		4,986
Stock-based compensation expense related to employee stock awards	7,948		7,948
Stock-based compensation expense related to employee stock purchases	504		504
Other comprehensive income (loss)	(94)				(94)
Net loss	(131,211)			(131,211)
Ending balance at Dec. 31, 2024	$ (28,973)	$ 8	$ 588,576	$ (618,008)	$ 451
Ending balance, Shares at Dec. 31, 2024		3,864,436