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Summary of significant accounting policies - Additional Information (Detail)
1 Months Ended 12 Months Ended
Aug. 19, 2024
shares
Jun. 30, 2024
Mar. 31, 2024
USD ($)
Dec. 31, 2024
USD ($)
Segment
shares
Dec. 31, 2023
USD ($)
shares
Dec. 31, 2022
USD ($)
Financing Sources [Line Items]            
Changes in fair value of common warrants reclassification adjustments         $ 2,200,000  
Re-measurement loss       $ 3,400 45,700  
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]       Chairman, President And Chief Executive Officer [Member]    
Cash equivalent qualification, description       The Company considers all highly liquid investments purchased with original maturities of 90 days or less at acquisition to be cash equivalents.    
Restricted cash       $ 110,000 70,000  
Credit-related losses recognized       0    
Impairment of right of use assets         724,000  
Impairment of long lived assets       0 0  
Dividends, common stock, cash       $ 0    
Expected dividend yield       0.00%    
Percentage of expected average remaining working lives of employees       10.00%    
Reduction to R&D expenses       $ 2,800,000 $ 1,600,000  
Stockholders' Equity, Reverse Stock Split 1-for-25          
Common Stock, Shares, Outstanding | shares 79,900,000     3,864,436 3,003,855  
Reduction in number of outstanding shares due to Reverse Stock Split | shares 3,300,000          
Number of fractional shares issued in connection with reverse stock split | shares 0          
Stockholders [Member]            
Financing Sources [Line Items]            
Stockholders' Equity, Reverse Stock Split   1-for-5 to 1-for-30        
Board of Directors [Member]            
Financing Sources [Line Items]            
Stockholders' Equity, Reverse Stock Split   1-for-25        
ABC Company            
Financing Sources [Line Items]            
Number of reportable segments | Segment       1    
Grant by the National Institutes of Health (NIH) for Research to Target Coronaviruses            
Financing Sources [Line Items]            
Government grants / contract awarded       $ 1,500,000 $ 1,400,000 $ 1,100,000
Government Assistance, Income, Increase (Decrease), Statement of Income or Comprehensive Income [Extensible Enumeration]       Research and Development Expense Research and Development Expense Research and Development Expense
Grant by the National Institute of Allergies and Infectious Diseases (NIAID) for Research to Target Coronaviruses            
Financing Sources [Line Items]            
Government grants / contract awarded     $ 1,300,000 $ 9,800,000 $ 8,500,000  
Government Assistance, Income, Increase (Decrease), Statement of Income or Comprehensive Income [Extensible Enumeration]     Research and Development Expense   Research and Development Expense  
Government contract, duration       2026 years    
General and Administrative (G&A) Expenses            
Financing Sources [Line Items]            
Impairment of right of use assets         $ 700,000