CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Income Statement [Abstract]
Revenue from collaborations	$ 2,571	$ 910
Operating expenses:
Research and development	31,676	22,869
General and administrative	6,452	5,781
Total operating expenses	38,128	28,650
Loss from operations	(35,557)	(27,740)
Interest and other income (expense), net	(5)	111
Loss before income tax expense	(35,562)	(27,629)
Income tax income (expense)	(53)	(45)
Net loss	(35,615)	(27,674)
Other comprehensive income (loss):
Unrealized loss on available-for-sale securities	(248)	(41)
Unrealized gain on pension plans		2
Other comprehensive loss	(248)	(39)
Comprehensive loss	$ (35,863)	$ (27,713)
Net loss per share, basic and diluted	$ (0.84)	$ (0.74)
Weighted average shares of common stock, basic and diluted	42,511,559	37,434,261