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Share-Based Compensation - Stock Option Activity (Details) - Stock options - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Number of shares    
Balance at the beginning (in shares) 8,049,474 6,921,180
Granted (in shares) 1,948,354 1,385,108
Exercised (in shares) 0 0
Forfeited (in shares) (163,414) (190,621)
Expired (in shares) (1,747) (526)
Balance at the end (in shares) 9,832,667 8,115,141
Vested options exercisable at the end (in shares) 3,271,151 1,858,885
Weighted average exercise price    
Balance at the beginning (in dollars per share) $ 2.14 $ 0.88
Granted (in dollars per share) 0.48 7.09
Exercised (in dollars per share) 0 0
Forfeited (in dollars per share) 3.20 1.23
Expired (in dollars per share) 1.08 1.23
Balance at the end (in dollars per share) 1.79 1.94
Vested options exercisable at the end (in dollars per share) $ 1.33 $ 0.86
Weighted average remaining contractual term    
Balance at the end (in years) 8 years 7 days 8 years 10 months 13 days
Vested options exercisable at the end (in years) 6 years 8 months 4 days 7 years 6 months 29 days
Aggregate intrinsic value (in thousands) $ 384 $ 42,151
Vested Options Exercisable $ 0 $ 11,662