X0508 4 2025-05-06 0000318154 AMGEN INC AMGN 0001798821 Griffith Peter H. ONE AMGEN CENTER DRIVE THOUSAND OAKS CA 91320 1 EVP & CFO 0 Common Stock 2025-05-06 4 A 0 3919 0 A 42246 D Nqso (Right to Buy) 270.44 2025-05-06 4 A 0 25334 270.44 A 2026-05-06 2035-05-06 Common Stock 25334 25334 D The Restricted Stock Units (RSUs) were granted pursuant to the Amgen Inc. Second Amended and Restated 2009 Equity Incentive Plan (the Equity Incentive Plan) and vest in four equal annual installments of 25% each, commencing on 5/6/2026. Vested RSUs will be paid in shares of the Company's common stock on a one-to-one basis. These shares include 398 Dividend Equivalents (DEs) granted pursuant to the Equity Incentive Plan and subject to a qualifying dividend reinvestment plan. DEs are credited on the reporting person's unvested RSUs and are paid out in shares of the Company's common stock on a one-to-one basis according to the vesting schedule, along with a cash payment for any remaining fractional amount. These non-qualified stock options were granted pursuant to the Equity Incentive Plan and vest and are exercisable in four equal annual installments of 25% each, commencing on 5/6/2026. /s/ Peter H. Griffith 2025-05-08