Segment Reporting (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2024 USD ($) segment	Dec. 31, 2023 USD ($)
Segment Reporting
Number of reportable segments | segment	1
AV-101 clinical trials	$ 19,740	$ 26,548
Employee costs	19,512	21,244
Professional fees and services	11,482	6,289
Stock-based compensation	11,311	11,906
Chemistry, manufacturing, and controls	11,110	14,339
Other segment items	1,515	1,140
Interest income	(5,042)	(5,945)
Consolidated net loss	$ 69,628	$ 75,521
Segment Reporting, Other Segment Item, Composition, Description	(a) Other segment items include rent and facilities related expenses.	(a) Other segment items include rent and facilities related expenses.