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STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Cash flows from operating activities:    
Net loss $ (129,468) $ (127,847)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 1,220 1,107
Stock-based compensation expense 25,037 20,213
Accretion of discount on investments, net (2,300) (8,103)
Changes in operating assets and liabilities:    
Prepaid expenses and other assets 1,787 143
Accounts payable and accrued other liabilities (7,246) 1,825
Net cash used in operating activities (110,970) (112,662)
Cash flows from investing activities:    
Acquisitions of property and equipment (712) (1,188)
Purchases of investments (399,819) (251,920)
Maturities of investments 252,500 275,245
Net cash (used in) provided by investing activities (148,031) 22,137
Cash flows from financing activities:    
Proceeds from issuance of common stock and pre-funded warrants 244,369 125,000
Issuance costs associated with financings (2,397) (168)
Proceeds from issuance of common stock under ESPP 1,313 1,084
Proceeds from stock option exercises 1,979 631
Net cash provided by financing activities 245,264 126,547
Net (decrease) increase in cash, cash equivalents and restricted cash (13,737) 36,022
Cash, cash equivalents and restricted cash at beginning of period 59,897 23,875
Cash, cash equivalents and restricted cash at end of period $ 46,160 $ 59,897