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Equity Incentive Plans and Stock-Based Compensation - Summary of Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
6 Months Ended
Jun. 30, 2022
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]  
Options outstanding, Beginning Balance 5,268,320
Options, Granted 1,757,035
Options, Exercised (46,889)
Options, Forfeited and cancelled (324,389)
Options outstanding, Ending Balance 6,654,077
Options, Exercisable 3,087,337
Weighted Average Exercise Price, Options outstanding Beginning Balance $ 14.16
Weighted Average Exercise Price, Granted 8.13
Weighted Average Exercise Price, Exercised 1.65
Weighted Average Exercise Price, Forfeited and Cancelled 16.94
Weighted Average Exercise Price, Options outstanding Ending Balance 12.51
Weighted Average Exercise Price, Exercisable $ 10.05
Weighted Average Remaining Contractual Term (in years), Options outstanding 8 years
Weighted Average Remaining Contractual Term (in years), Exercisable 6 years 10 months 24 days
Aggregate Intrinsic Value, Options outstanding $ 4,449
Aggregate Intrinsic Value, Exercisable $ 3,935