X0306 4 2019-11-15 0 0001616543 Senseonics Holdings, Inc. SENS 0001794362 Tressler Nick B. 20451 SENECA MEADOWS PARKWAY GERMANTOWN MD 20876-700 0 1 0 0 Chief Financial Officer Employee Stock Option (right to buy) 0.865 2019-11-15 4 A 0 300000 0.00 A 2029-11-14 Common Stock 300000 300000 D One-fourth of the shares vest on November 15, 2020, with the remaining shares vesting in 36 equal installments at the end of the calendar month for each month after November 15, 2020, subject to the reporting person's continuous service with the issuer as of the applicable vesting date. /s/ Mark Ballantyne, Attorney-in-fact 2019-11-19