X0306 4 2022-03-03 0 0001232524 Jazz Pharmaceuticals plc JAZZ 0001793243 Larkin Finbar 5TH FL, WATERLOO EXCHANGE WATERLOO RD DUBLIN 4 L2 IRELAND 0 1 0 0 SVP, Technical Operations Ordinary Shares 2022-03-03 4 A 0 4621 0.0 A 21209 D These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2022, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years. Includes 120 ordinary shares acquired under a Section 423 Employee Stock Purchase Plan on November 30, 2021. By: /s/Adam Guttmann, as attorney in fact For: Finbar Larkin 2022-03-09