The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ABBVIE INCCOM00287Y109224,7952,077,200SH SOLE 2,077,20000
ABIOMED INCCOM00365410042,232132,500SH SOLE 132,50000
ACCELERON PHARMA INCCOM00434H10843,775322,800SH SOLE 322,80000
ADAMAS PHARMACEUTICALS INCCOM00548A10610,5612,200,200SH SOLE 2,200,20000
ADICET BIO INCCOM00700210829,1682,230,000SH SOLE 2,230,00000
AFFIMED N VCOMN0104510810,2511,296,000SH SOLE 1,296,00000
ALDEYRA THERAPEUTICS INCCOM01438T10630,3182,552,000SH SOLE 2,552,00000
ALNYLAM PHARMACEUTICALS INCCOM02043Q10760,425427,969SH SOLE 427,96900
ALPHATEC HLDGS INCCOM NEW02081G20136,8542,334,000SH SOLE 2,334,00000
ALPINE IMMUNE SCIENCES INCCOM02083G10016,0171,511,000SH SOLE 1,511,00000
AMERICAN WELL CORPCL A03044L1051,22070,250SH SOLE 70,25000
ANNEXON INCCOM03589W1021,94970,000SH SOLE 70,00000
ARENA PHARMACEUTICALS INCCOM NEW04004760762,350898,550SH SOLE 898,55000
ARGENX SESPONSORED ADR04016X1015,50820,000SH SOLE 20,00000
ARVINAS INCCOM04335A105116,3561,760,300SH SOLE 1,760,30000
ARYA SCIENCES ACQU CORP IVCL AG316591085,236500,000SH SOLE 500,00000
ARYA SCIENCES ACQUISITION COCOM CL AG3166W1066,890500,000SH SOLE 500,00000
ASTRAZENECA PLCSPONSORED ADR046353108181,5033,650,500SH SOLE 3,650,50000
ATHIRA PHARMA INCCOM04746L10430,8721,677,845SH SOLE 1,677,84500
AURINIA PHARMACEUTICALS INCCOM05156V10223,1651,784,000SH SOLE 1,784,00000
AVANTOR INCCOM05352A100144,2194,985,100SH SOLE 4,985,10000
BAUSCH HEALTH COS INCCOM07173410760,0301,891,300SH SOLE 1,891,30000
BCLS ACQUISITION CORPCOM CL AG0904B1055,285500,000SH SOLE 500,00000
BCTG ACQUISITION CORPCOM05492W1033,336300,000SH SOLE 300,00000
BELLUS HEALTH INC NEWCOM NEW07987C20426,1026,797,400SH SOLE 6,797,40000
BIOHAVEN PHARMACTL HLDG CO LCOMG1119610571,7541,049,800SH SOLE 1,049,80000
BIOHAVEN PHARMACTL HLDG CO LCOMG1119690535,754523,100SHCallSOLE 523,10000
BIOVENTUS INCCOM CL A09075A10819,1661,254,333SH SOLE 1,254,33300
BLUEPRINT MEDICINES CORPCOM09627Y10953,088546,000SH SOLE 546,00000
BOLT BIOTHERAPEUTICS INCCOM09770210421,533654,294SH SOLE 654,29400
BRIDGEBIO PHARMA INCCOM10806X10250,210815,100SH SOLE 815,10000
CARDIFF ONCOLOGY INCCOM14147L10822,6662,447,700SH SOLE 2,447,70000
CARDINAL HEALTH INCCOM14149Y10888,8771,463,000SH SOLE 1,463,00000
CATALENT INCCOM14880610258,974560,000SH SOLE 560,00000
CHEMOCENTRYX INCCOM16383L10648,207940,800SH SOLE 940,80000
CHIMERIX INCCOM16934W10621,4972,230,000SH SOLE 2,230,00000
CIGNA CORP NEWCOM12552310032,635135,000SH SOLE 135,00000
CM LIFE SCIENCES II INCUNIT 02/25/20281258422034,310336,700SH SOLE 336,70000
CM LIFE SCIENCES INCCOM CL A18978W1098,190550,000SH SOLE 550,00000
COGENT BIOSCIENCES INCCOM19240Q2013,667417,710SH SOLE 417,71000
COLLEGIUM PHARMACEUTICAL INCCOM19459J10417,538740,000SH SOLE 740,00000
CULLINAN ONCOLOGY INCCOM23003110629,476707,359SH SOLE 707,35900
CURIS INCCOM NEW23126920023,2492,053,789SH SOLE 2,053,78900
DYNAVAX TECHNOLOGIES CORPCOM NEW26815820134,4053,500,000SH SOLE 3,500,00000
ESSA PHARMA INCCOM NEW29668H70882,5022,840,000SH SOLE 2,840,00000
EVELO BIOSCIENCES INCCOM2997341038,560800,000SH SOLE 800,00000
EXACT SCIENCES CORPCOM30063P10578,804598,000SH SOLE 598,00000
EYEPOINT PHARMACEUTICALS INCCOM NEW30233G2092,362232,504SH SOLE 232,50400
GRITSTONE ONCOLOGY INCCOM39868T10520,0112,122,064SH SOLE 2,122,06400
HARPOON THERAPEUTICS INCCOM41358P10629,4551,408,000SH SOLE 1,408,00000
HEALTH SCIENCES ACQ CORP 2ORD SHSG4411D1094,476400,000SH SOLE 400,00000
HEALTHCOR CATALIO ACQU CORPCL A SHSG441251055,000500,000SH SOLE 500,00000
HELIX ACQUISITION CORPCOM CL AG4444C1024,080400,000SH SOLE 400,00000
HORIZON THERAPEUTICS PUB LSHSG4618810153,475581,000SH SOLE 581,00000
I MABSPONSORED ADS44975P10364,4171,329,000SH SOLE 1,329,00000
IDEAYA BIOSCIENCES INCCOM45166A10234,5921,472,000SH SOLE 1,472,00000
IGM BIOSCIENCES INCCOM44958510822,470293,000SH SOLE 293,00000
IMMATICS N.VSHSN444451099,916884,600SH SOLE 884,60000
IMMUNOCORE HLDGS PLCADS45258D10523,414550,000SH SOLE 550,00000
INOVIO PHARMACEUTICALS INCCOM NEW45773H20137,1614,004,391SH SOLE 4,004,39100
INSTIL BIO INCCOM45783C10110,032400,000SH SOLE 400,00000
INTUITIVE SURGICAL INCCOM NEW46120E602103,008139,400SH SOLE 139,40000
KADMON HLDGS INCCOM48283N10637,1279,544,200SH SOLE 9,544,20000
KEZAR LIFE SCIENCES INCCOM49372L10011,3661,907,081SH SOLE 1,907,08100
KINIKSA PHARMACEUTICALS LTDCOM CL AG5269C10124,6311,330,700SH SOLE 1,330,70000
LIFESCI ACQUISITION II CORPCOM53229E1034,056400,000SH SOLE 400,00000
MARAVAI LIFESCIENCES HLDGS ICOM CL A56600D10798,4212,761,545SH SOLE 2,761,54500
MEDICUS SCIENCES ACQUISITIONUNIT 99/99/9999G5960S1165,122520,000SH SOLE 520,00000
MEDTRONIC PLCSHSG5960L103120,9891,024,200SH SOLE 1,024,20000
MERUS N VCOMN5749R10010,173487,000SH SOLE 487,00000
MIRATI THERAPEUTICS INCCOM60468T10581,487475,700SH SOLE 475,70000
NATERA INCCOM63230710440,169395,600SH SOLE 395,60000
NEUROCRINE BIOSCIENCES INCCOM64125C10950,706521,400SH SOLE 521,40000
NUVATION BIO INCCOM CL A67080N10178,6047,521,941SH SOLE 7,521,94100
NUVATION BIO INC*W EXP 07/07/20267080N11926799,999SH SOLE 99,99900
ONCOSEC MED INCCOM68234L30616,5523,470,000SH SOLE 3,470,00000
ORCHARD THERAPEUTICS PLCADS68570P10131,3474,317,800SH SOLE 4,317,80000
ORGANOGENESIS HLDGS INCCOM68621F10226,6631,463,403SH SOLE 1,463,40300
PHARVARIS N VCOMN6960510811,192400,000SH SOLE 400,00000
PHASEBIO PHARMACEUTICALS INCCOM71722410914,8264,285,000SH SOLE 4,285,00000
SANA BIOTECHNOLOGY INCCOM79956610424,511732,321SH SOLE 732,32100
SCYNEXIS INCCOM NEW81129220010,0341,263,769SH SOLE 1,263,76900
SEAGEN INCCOM81181C10480,247577,900SH SOLE 577,90000
SHATTUCK LABS INCCOM82024L10338,9001,330,385SH SOLE 1,330,38500
SI BONE INCCOM82570410918,373577,570SH SOLE 577,57000
SIGILON THERAPEUTICS INCCOM82657L10719,019850,968SH SOLE 850,96800
SOTERA HEALTH COCOM83601L10228,9791,161,000SH SOLE 1,161,00000
SYNDAX PHARMACEUTICALS INCCOM87164F10585,9973,846,000SH SOLE 3,846,00000
TERNS PHARMACEUTICALS INCCOM8808811078,800400,000SH SOLE 400,00000
TRILLIUM THERAPEUTICS INCCOM NEW89620X50643,1214,015,000SH SOLE 4,015,00000
VERTEX PHARMACEUTICALS INCCOM92532F10066,809310,900SH SOLE 310,90000
VESPER HEALTHCARE ACQSTN CORUNIT 99/99/999992538T2036,930600,000SH SOLE 600,00000
ZENTALIS PHARMACEUTICALS INCCOM98943L10754,8151,263,300SH SOLE 1,263,30000
ZIMMER BIOMET HOLDINGS INCCOM98956P10252,186326,000SH SOLE 326,00000