The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ABBVIE INCCOM00287Y109133,3821,522,800SH SOLE 1,522,80000
AC IMMUNE SASHSH002631057,5641,550,000SH SOLE 1,550,00000
ACCOLADE INCCOM00437E1021,55540,000SH SOLE 40,00000
ADAPTIMMUNE THERAPEUTICS PLSSPONDS ADR00653A10716,6362,084,700SH SOLE 2,084,70000
AKEBIA THERAPEUTICS INCCOM00972D10518,3837,324,000SH SOLE 7,324,00000
ALDEYRA THERAPEUTICS INCCOM01438T10610,5961,430,000SH SOLE 1,430,00000
ALPINE IMMUNE SCIENCES INCCOM02083G1007,120810,000SH SOLE 810,00000
AMARIN CORP PLCSPONS ADR NEW02311120618,9704,506,000SH SOLE 4,506,00000
AMERICAN WELL CORPCL A03044L1051,48250,000SH SOLE 50,00000
ANIKA THERAPEUTICS INCCOM03525510821,294601,700SH SOLE 601,70000
ANNEXON INCCOM03589W1021,13637,570SH SOLE 37,57000
ANTHEM INCCOM03675210347,379176,400SH SOLE 176,40000
APELLIS PHARMACEUTICALS INCCOM03753U10618,805623,300SH SOLE 623,30000
ARVINAS INCCOM04335A10531,8331,348,300SH SOLE 1,348,30000
ARYA SCIENCES ACQUISITION COCOM CL AG316551145,408500,000SH SOLE 500,00000
ATHIRA PHARMA INCCOM04746L10418,9461,026,342SH SOLE 1,026,34200
AURINIA PHARMACEUTICALS INCCOM05156V10252,5113,564,900SH SOLE 3,564,90000
AVANTOR INCCOM05352A100102,6084,562,400SH SOLE 4,562,40000
AXSOME THERAPEUTICS INCCOM05464T1048,408118,000SH SOLE 118,00000
BAXTER INTL INCCOM07181310949,860620,000SH SOLE 620,00000
BCTG ACQUISITION CORPCOM05492W1033,108300,000SH SOLE 300,00000
BERKELEY LTS INCCOM0843101011,90925,000SH SOLE 25,00000
BIOGEN INCCOM09062X10389,388315,100SH SOLE 315,10000
BIOGEN INCCOM09062X90360,736214,100SHCallSOLE 214,10000
BIOHAVEN PHARMACTL HLDG CO LCOMG1119610583,4861,284,200SH SOLE 1,284,20000
BIONTECH SESPONSORED ADS09075V10214,261206,000SH SOLE 206,00000
BIOXCEL THERAPEUTICS INCCOM09075P10523,328538,000SH SOLE 538,00000
BOSTON SCIENTIFIC CORPORATIONCOM10113710736,953967,100SH SOLE 967,10000
BRISTOL-MYERS SQUIBB CORIGHT 99/99/999911012215751,04122,684,932SH SOLE 22,684,93200
CATALENT INCCOM14880610227,248318,100SH SOLE 318,10000
CHANGE HEALTHCARE INCCOM15912K10036,6742,527,500SH SOLE 2,527,50000
CLOVIS ONCOLOGY INCCOM1894641005,8301,000,000SH SOLE 1,000,00000
COLLEGIUM PHARMACEUTICAL INCCOM19459J10420,8281,000,400SH SOLE 1,000,40000
DYNAVAX TECHNOLOGIES CORPCOM NEW2681582018,7482,025,000SH SOLE 2,025,00000
ESSA PHARMA INCCOM NEW29668H70814,4062,087,800SH SOLE 2,087,80000
EXELIXIS INCCOM30161Q10418,807769,200SH SOLE 769,20000
HARPOON THERAPEUTICS INCCOM41358P10619,9071,171,700SH SOLE 1,171,70000
HEALTH SCIENCES ACQ CORP 2ORD SHSG4411D1094,400400,000SH SOLE 400,00000
HORIZON THERAPEUTICS PUB LSHSG4618810172,258930,200SH SOLE 930,20000
HUMANA INCCOM44485910221,31551,500SH SOLE 51,50000
I MABSPONSORED ADS44975P10363,0201,340,000SH SOLE 1,340,00000
IDEAYA BIOSCIENCES INCCOM45166A10213,1981,050,800SH SOLE 1,050,80000
INOZYME PHARMA INCCOM45790W1081,62661,855SH SOLE 61,85500
IOVANCE BIOTHERAPEUTICS INCCOM46226010026,303799,000SH SOLE 799,00000
ITEOS THERAPEUTICS INCCOM46565G1048,141330,000SH SOLE 330,00000
KADMON HLDGS INCCOM48283N10635,3989,030,000SH SOLE 9,030,00000
MEDTRONIC PLCSHSG5960L10318,810181,000SH SOLE 181,00000
MERCK & CO. INCCOM58933Y10594,9201,144,300SH SOLE 1,144,30000
MERSANA THERAPEUTICS INCCOM59045L10614,103757,400SH SOLE 757,40000
MIRATI THERAPEUTICS INCCOM60468T10545,664275,000SH SOLE 275,00000
NATERA INCCOM63230710436,366503,400SH SOLE 503,40000
NURIX THERAPEUTICS INCCOM67080M1031,74650,000SH SOLE 50,00000
OAK STR HEALTH INCCOM67181A1075,344100,000SH SOLE 100,00000
OUTSET MED INCCOM6901451075,000100,000SH SOLE 100,00000
PANACEA ACQUISITION CORPUNIT 99/99/99996981022093,600300,000SH SOLE 300,00000
PFIZER INCCOM717081903238,5506,500,000SHCallSOLE 6,500,00000
PMV PHARMACEUTICALS INCCOM69353Y1035,325150,000SH SOLE 150,00000
QUEST DIAGNOSTICS INCCOM74834L10046,025402,000SH SOLE 402,00000
QUIDEL CORPCOM74838J10138,804176,879SH SOLE 176,87900
RELAY THERAPEUTICS INCCOM75943R1021,27830,000SH SOLE 30,00000
SEATTLE GENETICS INCCOM812578102103,931531,100SH SOLE 531,10000
SYNDAX PHARMACEUTICALS INCCOM87164F10527,3671,854,100SH SOLE 1,854,10000
TAYSHA GENE THERAPIES INCCOM SHS8776191068,781392,000SH SOLE 392,00000
THERMO FISHER SCIENTIFIC INCCOM88355610252,232118,300SH SOLE 118,30000
TRILLIUM THERAPEUTICS INCCOM NEW89620X50624,8111,746,000SH SOLE 1,746,00000
VESPER HEALTHCARE ACQSTN CORUNIT 99/99/999992538T2036,156600,000SH SOLE 600,00000
ZENTALIS PHARMACEUTICALS INCCOM98943L10729,556904,119SH SOLE 904,11900
ZYMEWORKS INCCOM98985W10211,398244,700SH SOLE 244,70000