The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | |||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | ||||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | (to the nearest dollar) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2SEVENTY BIO INC | COMMON STOCK | 901384107 | BBG00YV1J631 | 3,927,867 | 1,002,007 | SH | DFND | 6 | 1,002,007 | 0 | 0 | |
| ACELYRIN INC | COM | 00445A100 | 23,014,608 | 2,262,990 | SH | DFND | 6 | 2,262,990 | 0 | 0 | ||
| BLACK DIAMOND THERAPEUTICS I | COM | 09203E105 | BBG00MS4Y0X8 | 2,066,400 | 720,000 | SH | DFND | 6 | 720,000 | 0 | 0 | |
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | BBG001V11BV0 | 4,664,835 | 92,888 | SH | DFND | 6 | 92,888 | 0 | 0 | |
| COMPASS THERAPEUTICS INC | COM | 20454B104 | BBG00LPXKF34 | 5,574,532 | 2,829,712 | SH | DFND | 6 | 2,829,712 | 0 | 0 | |
| CULLINAN ONCOLOGY INC | COM | 230031106 | BBG00HW2DGR3 | 30,898,410 | 3,414,189 | SH | DFND | 6 | 3,414,189 | 0 | 0 | |
| DIREXION SHS ETF TR | DAILY S&P BIOTEC | 25460G716 | BBG0099SHGK3 | 4,635,000 | 225,000 | SH | DFND | 6 | 225,000 | 0 | 0 | |
| DISC MEDICINE INC | COM | 254604101 | BBG00W9MJL04 | 1,174,500 | 25,000 | SH | DFND | 6 | 25,000 | 0 | 0 | |
| FREELINE THERAPEUTICS HLDGS | SPONSORED ADS | 35655L206 | 372,613 | 86,654 | SH | DFND | 6 | 86,654 | 0 | 0 | ||
| GRAPHITE BIO INC | COM | 38870X104 | BBG00XDH4P05 | 572,726 | 230,938 | SH | DFND | 6 | 230,938 | 0 | 0 | |
| IKENA ONCOLOGY INC | COM | 45175G108 | BBG00XZY4TH8 | 9,443,445 | 2,180,934 | SH | DFND | 6 | 2,180,934 | 0 | 0 | |
| INOZYME PHARMA INC | COM | 45790W108 | BBG00J7QJMD0 | 5,334,112 | 1,270,027 | SH | DFND | 6 | 1,270,027 | 0 | 0 | |
| KEROS THERAPEUTICS INC | COM | 492327101 | BBG00H1HP9H8 | 12,995,340 | 407,633 | SH | DFND | 6 | 407,633 | 0 | 0 | |
| LARIMAR THERAPEUTICS INC | COM | 517125100 | BBG001V0GD97 | 13,487,148 | 3,414,468 | SH | DFND | 6 | 3,414,468 | 0 | 0 | |
| MINERALYS THERAPEUTICS INC | COM | 603170101 | BBG00ZXN1GR9 | 5,405,284 | 568,379 | SH | DFND | 6 | 568,379 | 0 | 0 | |
| MOONLAKE IMMUNOTHERAPEUTICS | CLASS A ORD | 61559X104 | BBG00XQZQVP7 | 3,420,000 | 60,000 | SH | DFND | 6 | 60,000 | 0 | 0 | |
| OMEGA THERAPEUTICS INC | COMMON STOCK | 68217N105 | BBG00WCNQZQ1 | 2,270,146 | 1,055,882 | SH | DFND | 6 | 1,055,882 | 0 | 0 | |
| ORCHARD THERAPEUTICS PLC | SPON ADS NEW | 68570P200 | 14,034,773 | 12,315,654 | SH | DFND | 6 | 12,315,654 | 0 | 0 | ||
| OVID THERAPEUTICS INC | COM | 690469101 | BBG009F0TD85 | 3,320,916 | 864,822 | SH | DFND | 6 | 864,822 | 0 | 0 | |
| PLIANT THERAPEUTICS INC | COM | 729139105 | BBG00C8083P2 | 52,266,211 | 3,014,199 | SH | DFND | 6 | 3,014,199 | 0 | 0 | |
| PLIANT THERAPEUTICS INC | COM | 729139105 | BBG00C8083P2 | 55,000 | 137,500 | SH | Call | DFND | 6 | 137,500 | 0 | 0 |
| PRECISION BIOSCIENCES INC | COM | 74019P108 | BBG008NSBPW2 | 207,043 | 606,629 | SH | DFND | 6 | 606,629 | 0 | 0 | |
| RALLYBIO CORP | COM | 75120L100 | BBG011PFKG07 | 1,316,774 | 390,734 | SH | DFND | 6 | 390,734 | 0 | 0 | |
| REPARE THERAPEUTICS INC | COM | 760273102 | BBG00V5N3XG2 | 35,837,422 | 2,966,674 | SH | DFND | 6 | 2,966,674 | 0 | 0 | |
| REPARE THERAPEUTICS INC | COM | 760273102 | BBG00V5N3XG2 | 157,500 | 50,000 | SH | Call | DFND | 6 | 50,000 | 0 | 0 |
| SAGIMET BIOSCIENCES INC | COM SER A | 786700104 | BBG0020584Z8 | 3,069,810 | 348,842 | SH | DFND | 6 | 348,842 | 0 | 0 | |
| SYROS PHARMACEUTICALS INC | COM NEW | 87184Q206 | 5,119,170 | 1,299,359 | SH | DFND | 6 | 1,299,359 | 0 | 0 | ||
| ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 | BBG001V2MJJ2 | 7,664,750 | 215,000 | SH | DFND | 6 | 215,000 | 0 | 0 | |